نتایج جستجو برای: dat1
تعداد نتایج: 319 فیلتر نتایج به سال:
Objectives: Dyshomeostasis of the dopaminergic system is implicated in the pathophysiology of eating disorders (EDs). We have previously reported an association between 3'-UTR VNTR (three prime untranslated region variable number of tandem repeat) of the Dopamine Transporter 1 (DAT1) gene and ED with binge eating behavior (EDBEB). Here we investigated whether variants in the coding region of th...
هدف: نقص در سامانه ی نقل و انتقال دوپامین، می تواند به عنوان یکی از علل بیماری اسکیزوفرنی مطرح شود. ترانسپورتر دوپامین ( dat1 ) باز جذب دوپامین از انتهای سیناپس های عصبی را بر عهده دارد، بنابراین نقش مهمی را در تنظیم نقل و انتقال دوپامین ایفا می کند. در این تحقیق ، همراهی احتمالی پلی مورفیسم 67t/a- واقع در پروموترژن dat1 با بیماری اسکیزوفرنیا به وسیله روش توصیفی مورد بررسی قرار می گیرد. روش ب...
BACKGROUND Mothers' positive emotions expressed about their children with attention deficit/hyperactivity disorder (ADHD) are associated with a reduced likelihood of comorbid conduct problems (CP). We examined whether this association with CP, and one with emotional problems (EMO), is moderated by variants within three genes, previously reported to be associated with ADHD and to moderate the im...
مقدمه: اسکیزوفرنی نوعی از بیماری های روانی است که 1% جمعیت را تحت تأثیر قرار می دهد. دوپامین یکی از انتقال دهنده های اصلی در مغز است و رسپتورهای آن با تعدادی از اختلالات روانی مانند اسکیزوفرنی در ارتباط هستند. هیپرمتیلاسیون dna در نواحی پروموتر ژن ها نقش اساسی در کاهش بیان ژن های دخیل در بعضی از بیماری ها را دارد. رسپتورهای دوپامین در خاطره اپیزوتیک، ادراک، آگاهی و احساسات دخیل هستند که این اعم...
The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with the TaqI A1 allele. Energy intake was greater for individuals high in food reinf...
Epigenetic processes have been implicated in neuronal plasticity following repeated cocaine application. Here we measured DNA methylation at promoter CpG sites of the dopamine transporter (DAT1) and serotonin transporter (SERT) and neurokinin3-receptor (NK3-R)-receptor (TACR3) coding genes in marmoset monkeys after repeated cocaine injections in a conditioned place preference paradigm. We found...
Publised in Periodica Polytechnika 1999 Abstract The present situation in Hungary is introduced in the field of GIS data exchange in this paper. Most of the data exchanges concentrate on map data (graphical data) without attributes. The new Hungarian standard DAT1 (MSz 7772-1) has changed the situation. It involves map, topology and attribute data as well. This is the official data exchange for...
BACKGROUND Dopamine plays an important role in orienting and the regulation of selective attention to relevant stimulus characteristics. Thus, we examined the influences of functional variants related to dopamine inactivation in the dopamine transporter (DAT1) and catechol-O-methyltransferase genes (COMT) on the time-course of visual processing in a contingent negative variation (CNV) task. M...
Although educational attainment has been found to be moderately heritable, research has yet to explore candidate genes for it. Drawing on data from the National Longitudinal Study of Adolescent Health, in the current study, we examined the association between polymorphisms in three dopaminergic genes (DAT1, DRD2, and DRD4), a dopamine index, and educational attainment. Statistically significant...
In this tudy, it was aimed to investigate the association/s between dopamine transporter gene (DAT1), receptor D1 (DRD1), D2 (DRD2), D3 (DRD3), D4 (DRD4) variants and adult Attention Deficit Hyperactivity Disorder (ADHD). A prospective analytical case control study. total of 128 ADHD cases 100 non-ADHD controls from Western population Turkey were included in DNA isolated peripheral blood. Genot...
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