The present study was carried out to determine the phytochemical profile and antibacterial activity of Andrographis paniculata and Datura metel extracts. For the present investigation, extracts of A. paniculata and D.metel were prepared by extraction in methanol, chloroform, acetone and benzene and were compared for their antibacterial activity. The antibacterial activities were assessed by mea...

Xanthine oxidase inhibitory activity has been reported from different plants such as Cinnamomum cassia, Chrysanthemum indicum, Lycopus europaeus, Polygonum cuspidatum, Acacia confuse, Coccinia grandis, Datura metel, Strychnos nux-vomica, Vitex negundo, Coccinia grandis, Vitex negundo, Fraxinus angustifolia, Pistacia lentiscus, Hyptis obtusiflora, H. lantanaefolia, Artemisia vulgaris, Caesalpini...

Efficacy of seven fungicides and seven plant extracts were evaluated against two pathogenic species of fungi isolated from Senna alata L. in vitro. The isolated fungi were Colletotrichum gloeosporioides (Penz.) Sacc. and Pestalotiopsis guepinii (Desm.) Stay. Seven fungicides Acrobate MZ, Bavistin 50 WP, Indofil M-45, MC Sulphur 80 WP, Ridomil MZ Gold, Sulcox 50 WP and Tall 25 EC at 100, 200, 30...

The production of prostaglandin D2 (PGD2) by rat peritoneal mast cells incubated with N-acetyl glucosamine (GlcNAc) oligomer-specific Datura stramonium agglutinin (DSA) for 10 min in the presence of 0.3 mM Ca2+ was examined. Previously, our group reported that the incubation of rat mast cells with DSA (5 - 100 microg/ml) under similar conditions resulted in a calcium influx and histamine releas...

Pharmacognosy Research,2022,14,2,146-152.DOI:10.5530/pres.14.2.21Published:April 2022Type:Original ArticleAuthors:Shakila Ramachandran, Saravanan Meenatchisundaram, Subashini Subramanian, Sujith Thatipelli, Achintya Kumar Mandal, and Rajesh Allu Author(s) affiliations:Shakila Ramachandran1,*, Meenatchisundaram2, Subramanian3, Thatipelli4, Mandal5, Allu6 Department of Chemistry, Siddha Central R...

Datura is known as a medicinal plant and hallucinogen all over the world. rich source of alkaloids such Hyoscyamine, hyoscine, scopolamine, atropine, with anolides (lactones) other tropanes. Based on presence alkaloids, formulations containing exhibit antibacterial, antioxidant, herbicidal, antifungal, antiviral antiulcer properties. Historically, has been employed in treatment skin disorders, ...

Hyoscyamine, anisodamine and scopolamine are tropane alkaloids present in some Solanaceae species used modern medicine. L-Hyoscyamine is hydroxylated to 6β-hydroxyhyoscyamine (anisodamine) then epoxidated by the dual action of hyoscyamine 6β-hydroxylase (H6H), a 2-oxoglutarate dependent dioxygenase. A natural mutation Gly-220 residue Cys was previously shown be associated with loss function H6H...

Leakages of amino acids and/or fluorescent material as functions of temperature between 15 and 40 C are reported for imbibed seeds of Avena fatua L., Lactuca sativa L., Barbarea vulgaris R. Br., Amaranthus albus L., Abutilon theophrasti Medic., Lychnis alba Mill., Daucus carota L., Setaria faberi Herrm., Setaria viridis (L.) Beauv., and Datura stramonium L. The leakage indicates prominent incre...