نتایج جستجو برای: dcc model
تعداد نتایج: 2105734 فیلتر نتایج به سال:
DCC (Deleted in Colorectal Carcinoma) has been demonstrated to constrain tumor progression by inducing apoptosis unless engaged by its ligand netrin-1. This has been shown in breast and colorectal cancers; however, this tumor suppressive function in other cancers is not established. Using a transgenic mouse model, we report here that inhibition of DCC-induced apoptosis is associated with lympho...
The deleted in colorectal cancer (DCC) gene, a candidate tumor suppressor gene on chromosome 18q21, encodes a neural cell adhesion molecule family protein that is most highly expressed in the nervous system. To address the hypothesis that DCC may play a role in glioma development and/or progression, we examined DCC expression by immunohistochemistry in 57 resected human astrocytic tumors. Overa...
Tropical deep convective clouds (DCC) are an excellent invariant target for vicarious calibration of satellite visible (VIS) and near-infrared (NIR) solar bands. The DCC technique (DCCT) is a statistical approach that collectively analyzes all identified DCC pixels on a monthly basis. The DCC reflectance in VIS and NIR spectrums is mainly a function of cloud optical depth, and provides a stable...
The spinal neural circuit contains inhibitory (CINi) and excitatory (CINe) commissural interneurons with axons crossing the mid-line. Direction of these axons to the other side of the cord is controlled by axon guidance molecules, such as Netrin-1 and DCC. The cord also contains glutamatergic interneurons, whose axon guidance involves the EphA4 receptor. In EphA4 knockout (KO) and Netrin-1 KO m...
We address the issue of whether a region of disordered chiral condensate (DCC), in which the chiral condensate has components along the pion directions, can form. We consider a system going through the chiral phase transition either via a quench, or via relaxation of the high temperature phase to the low temperature one within a given time scale (of order ∼ 1fm/c). We use a density matrix based...
BACKGROUND Biventricular direct cardiac compression (DCC) has the potential to support the failing heart without the complications associated with a blood/device interface encountered with the use of current ventricular assist devices. A clinically designed DCC device that provides compression pressure around the base of the heart in synchrony with native ventricular contractions was evaluated ...
This paper introduces the scalar DCC-HEAVY and DECO-HEAVY models for conditional variances correlations of daily returns based on measures realized built from intraday data. Formulas multi-step forecasts are provided. Asymmetric versions developed. An empirical study shows that in terms HEAVY outperform BEKK-HEAVY model covariances BEKK, DCC, DECO multivariate GARCH exclusively
Cloud computing datacenters provide millions of virtual machines in actual cloud markets. In this context, Virtual Machine Placement (VMP) is one of the most challenging problems in cloud infrastructure management, considering the large number of possible optimization criteria and different formulations that could be studied. In the existing literature, the VMP problem is mostly formulated as a...
This study investigated the effects of stable transfection of the exogenous wild-type DCC gene on growth of the human colorectal carcinoma cell line SW1116 in vitro. The DCC gene was amplified from normal human colon tissue by reverse transcription-polymerase chain reaction and used to construct a recombinant expression plasmid, pcDNA3.1(+)-DCC. DCC-negative SW1116 cells were transfected with p...
The guidance molecule Netrin and its receptor DCC (deleted in colorectal cancer) attract commissural axons toward the midline en route to their final destination. To test whether these molecules can also guide dendrites, we studied the contralateral dendrites of zebrafish octavolateralis efferent (OLe) neurons, which are unusual in that they navigate toward and cross the midline. We found that,...
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