BACKGROUND Deep vein thrombosis (DVT) is a relatively prevalent disease which causes high costs due to the required diagnostic tests, specialized treatments, and hospital admission. In recent decades, implementation of thromboprophylaxis protocols has significantly reduced the incidence of thromboembolism in hospitals. The present study aimed to compare the incidence of venous thromboembolism b...

Venous thromboembolism, which includes deep venous thrombosis and pulmonary embolism, is a potentially preventable condition in children. In adults, pharmacologic prophylaxis has been shown to significantly reduce the incidence of venous thromboembolism in distinct patient cohorts. However, pediatric randomized controlled trials have failed to demonstrate the efficacy of pharmacologic prophylax...

BACKGROUND Venous thromboembolism has genetic determinants, but population-based data on familial risks are limited. OBJECTIVES To examine the familial risk of venous thromboembolism. METHODS We undertook a nationwide study of a cohort of patients with deep venous thrombosis or pulmonary embolism born after 1952. We used the Danish National Registry of Patients covering all Danish hospitals...

Venous thromboembolism is an increasingly recognised complication in the community and in hospital in-patients. Nowadays, most physicians are familiar with the algorithmic approach to the management of suspected deep vein thrombosis. However, a lack of understanding remains with regard to certain aspects of the diagnostic and treatment pathways, which has resulted in the wrong information being...

International travel has become increasingly common and accessible, hence, about two billion passengers undertake international and domestic air travel each year. Venous thromboembolism (VTE) is a serious public health disorder which may occur following prolonged travel, especially after air travel. A direct relation between VTE development and prolonged travels has been documented, while some ...

UNLABELLED Introduction. Controversy remains over the optimal length of anticoagulation following idiopathic venous thromboembolism. We sought to determine if a longer, finite course of anticoagulation offered additional benefit over a short course in the initial treatment of the first episode of idiopathic venous thromboembolism. Data Extraction. Rates of deep venous thrombosis, pulmonary embo...

The scientific debate on oral contraceptives (OCs) therapy and thrombotic diseases continues unabated. This retrospective casecontrol study was intended to evaluate the age specific effects of oral contraceptives and smoking on the risk of deep venous thrombosis, pulmonary thromboembolism and arterial thombosis in women under 50 years. The study included evaluation of registry records of Bulgar...

BACKGROUND AND OBJECTIVES The rate of post-operative asymptomatic deep-vein thrombosis in Asian patients remains uncertain. The aim of this study was to estimate the rate of venous thromboembolism, including asymptomatic deep-vein thrombosis, undergoing hip or knee surgery and not receiving pharmacological thromboprophylaxis. DESIGN AND METHODS This was a prospective observational study of a ...

OBJECTIVE To evaluate the association between use of hormone replacement therapy and the risk of idiopathic venous thromboembolism. DESIGN Population based case-control study. SETTING Population enrolled in the General Practice Research Database, United Kingdom. SUBJECTS A cohort of 347,253 women aged 50 to 79 without major risk factors for venous thromboembolism was identified. Cases wer...

OBJECTIVE To summarise the evidence supporting the use of rapid d-dimer testing combined with estimation of clinical probability to exclude the diagnosis of deep venous thrombosis among outpatients. DATA SOURCES Medline (June 1993 to December 2003), the Database of Abstracts and Reviews (DARE), and reference lists of studies in English. SELECTION OF STUDIES We selected 12 studies from among...