INTRODUCTION The prognosis of dengue depends on early diagnosis and treatment, which can help prevent severe forms whose characteristics were evaluated here. METHODS A cross-sectional study was conducted involving dengue cases in Vitória, State of Espírito Santo, Brazil, in 2011. RESULTS Two health regions registered 56.3% of 371 cases of severe dengue. Of these cases, 21.3% presented with ...

There are four dengue virus serotypes, based on molecular analysis. Each serotype is divided to several different genotypes, such as there are 5 genotypes in dengue virus serotype 3 (DENV-3), in which genotype II was confirmed to be the main etiology cause the big dengue fever/dengue hemorrhagic fever outbreak in Vietnam 1998. Molecular epidemiological study was carried out on DENV-3, which cau...

OBJECTIVE To assess the validity of dengue fever reports and how they relate to the definition of case and severity. METHODS Diagnostic test assessment was conducted using cross-sectional sampling from a universe of 13,873 patients treated during the fifth epidemiological period in health institutions from 11 Colombian departments in 2013. The test under analyses was the reporting to the Nation...

A dengue fever surveillance study was conducted at three medical facilities located in the low-income district of San Javier in Medellin, Colombia. During March 2008 to 2009, 781 patients with fever regardless of chief complaint were recruited for acute dengue virus infection testing. Of the 781 tested, 73 (9.3%) were positive for dengue infection. Serotypes DENV-2 (77%) and -3 (23%) were detec...

Cross-reactive T cell responses induced by a primary dengue virus infection may contribute to increased disease severity following heterologous infections with a different virus serotype in a phenomenon known as the original antigenic sin. In this study, we developed and analyzed in-host models of T cell responses to primary and secondary dengue virus infections that considered the effect of T ...

It manifests with wide range of severity from asymptomatic mild febrile illness to life threatening disease including Dengue Haemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Classic dengue fever frequently presents with fever, headache, myalgias, arthalgias, nausea, and vomiting and maculopapular skin rash. According to the WHO report, the mortality in untreated cases of dengue fever w...

Dengue fever is the world's most important viral hemorrhagic fever disease, the most geographically wide-spread of the arthropod-born viruses, and it causes a wide clinical spectrum of disease. We report a case of dengue hemorrhagic fever complicated by acute hepatitis. The initial picture of classical dengue fever was followed by painful liver enlargement, vomiting, hematemesis, epistaxis and ...

Calcutta has a long experience of recurrent epidemics of Dengue fever(l,2). Serological surveys carried out during 1960 by Sarkar et al.(3) and a re-survey in 1966(4) showed a high endemicity of Dengue in Calcutta. Calcutta experienced Dengue Hemorrhagic Fever (DHF) for the first time during 1963-65(5,6). During this epidemic, Dengue viruses 2 and 4 were isolated^). Dengue hemorrhagic fever is ...

Dengue fever is a major public health problem in India. Dengue haemorrhagic fever (DHF), a more serious form of disease, occurs when a person previously infected with dengue is reinfected with a different serotype. Besides common manifestations pleural effusion, pneumonitis, haemoptysis and pulmonary haemorrhage have rarely been seen. We report a case of 30 years old male, who developed pulmona...

flaviviridae are viruses that cause several diseases including dengue fever, japanese encephalitis, murray valley encephalitis, tick-borne encephalitis, west nile encephalitis, yellow fever and hepatitis c virus infection. members of this family have monopartite, linear, single-stranded rna genomes of positive polarity, 9.6-12.3 kb in length. here, we have analyzed the codon usage of 13 species...