The presence of odontoblasts in dentinal tubules has been noted by numerous investigators. One of the first to describe their presence was B. Orban (l Dent Res 20:553-557, 1941). The cells were in tubules associated with forceps marks on the root surfaces. Odontoblasts in dentinal tubules have been reported due to various types of trauma to pulps. Cavity preparation (V. E. JAMES and I. SCHOUR, ...

Dent disease has multiple defects attributed to proximal tubule malfunction including low-molecular-weight proteinuria, aminoaciduria, phosphaturia, and glycosuria. To understand the changes in kidney function of the Clc5 chloride/proton exchanger gene knockout mouse model of Dent disease, we examined gene expression profiles from proximal S1 and S2 tubules of mouse kidneys. We found many chang...

Since crown size reduction has been observed in 47-trisomy G (M. M. COHEN and R. A. WINER, J Dent Res 44:197-208, 1965; M. M. COHEN, S. M. GARN, and M. A. GECIAUSKAS, J Dent Res 49:460, 1970) with delayed tooth formation timing (S. M. GARN, C. W. STIMSON, and A. B. LEWIS, J Dent Res 49:640, 1970), it is useful to compare the magnitude of crown size reduction with the magnitude of body size redu...

This paper explains why seemingly irrational overconŽdent behavior can persist. Information aggregation is poor in groups in which most individuals herd. By ignoring the herd, the actions of overconŽdent individuals (“entrepreneurs”) convey their private information. However, entrepreneurs make mistakes and thus die more frequently. The socially optimal proportion of entrepreneurs trades off th...

The influence of visual effects for tactile sensation in augmented reality environment is experimentally evaluated. Texture and dent are used as the visual effects. Pitch and brightness difference in stripe textures are used as parameters. Radius and depth of dent are also utilized. At first, preliminary experiment on a few subjects was conducted to find the change in tactile sensation by visua...

Experimental evidence suggests that people tend to be overcon dent in the sense that they overestimate the accuracy of their private information. In this paper we show that risk-averse principals might prefer overcon dent agents in various strategic interactions because these agents help diversify the aggregate risk. This may help understanding why successful analysts and entrepreneurs tend to ...

The labour economics literature on signalling assumes workers know their own abilities. Well-settled experimental evidence contradicts that assumption: in the absence of hard facts, subjects are on average overcon ̄dent. First we show that in any equilibrium of any signalling model, overcon ̄dence cannot make players better o®. In order to obtain more detailed predictions, we then introduce a spe...

Severe acute respiratory syndrome coronavirus (SARS-COV-2) presented with pulmonary symptoms and various extra manifestations including dermatological like urticarial, acralvascular lesion erythematous maculopapular rash, vesicular rash. Herpes zoster is a painful rash resulting from reactivation of varicella-zoster (VZ) virus that also causative agent chickenpox. The incidence HZ infection (HZ...

Mutations of OCRL1 are associated with both the Lowe oculocerebrorenal syndrome, a multisystemic and Dent-2 disease, a renal tubulopathy. We have identified a mutation in 130 Lowe syndrome families and 6 affected by Dent-2 disease with 51 of these mutations being novel. No founding effect was evidenced for recurrent mutations. Two mutations initially reported as causing Dent-2 disease were iden...