Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp ni...

Background: Pulp stones are calcification in the dental pulp which can be present either in deciduous or permanent teeth. Exact causes of pulp stones are not known and several elements have been associated. It can be seen in healthy, diseased or as a part of various syndromes. Frequency of pulp stones fluctuated from 8 to 95% depending on the population studied. Our study is an attempt to know ...

Human deciduous and permanent teeth exhibit different developmental processes, morphologies, histological characteristics and life cycles. In addition, their pulp tissues react differently to external stimuli, such as the pulp sensitivity test, dental trauma and pulp therapy materials. These suggest differences in gene expression and regulation, and in this study we compared gene-expression pro...

Stem cells are primitive cells that can differentiate and regenerate organs in different parts of the body such as heart, bones, muscles and nervous system. This has been a field of great clinical interest with immense possibilities of using the stem cells in regeneration of human organ those are damaged due to disease, developmental defects and accident. The knowledge of stem cell technology i...

Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. Meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. In enzymatic digestion method extracted teeth as denta...

this article describes successful use of calcium-enriched mixture (cem) cement and biodentine in apexogenesis treatment in two 8-year-old patients, one with immature permanent molar diagnosed primarily with irreversible pulpitis and the other with partially vital maxillary central incisor. after access cavity preparation, partial pulpotomy in molar and full pulpotomy in central was performed, a...

this case report presents endodontic management of a mandibular lateral incisor with three canals using surgical dental operating microscope. this study describes the root canal variation of mandibular lateral incisor and highlights the importance of surgical operating microscope in detecting an unusual canal morphology.

OBJECTIVE The aim of this study is to analyze the effects of combining cone beam computed tomography (CBCT) technology with visual root canal recurrence in the treatment of elderly patients with dental pulp disease. PATIENTS AND METHODS 56 cases of elderly patients with dental pulp disease were contiguously selected, and randomly divided into the control group (70 teeth from 27 patients) and ...

www.endojournal.com.ar 540 Dental pulp is a highly vascularized and innervated tissue. The neural component of the pulp tissue consists of motor and sensory nerve fibers, the latter coming from the cranial nerve V; all stimuli that provoke these fibers will result in a painful sensation. Dental pulp tissue is not the only tissue with this characteristic. The eye cornea and the tympanic membrane...

BACKGROUND Dental pulp is used for PCR-based detection of DNA derived from host and bacteremic microorganims. Current protocols require odontology expertise for proper recovery of the dental pulp. Dental pulp specimen exposed to laboratory environment yields contaminants detected using universal 16S rDNA-based detection of bacteria. METHODOLOGY/PRINCIPAL FINDINGS We developed a new protocol b...