Background: Facial repigmentation is the main primary outcome measure of most trials assessing new treatments for vitiligo. Objective: To assess validity and reliability an objective measurement method percent depigmentation vitiligo lesions on face. Methods: Multicentric cross-sectional prospective trial. 22 consecutive patients presenting with facial were included. Depigmentation was analyzed...

Purpose: To assess the ability of radiofrequency (RF) microporation to promote trans-epidermal delivery of arbutin. Methods: To investigate the enhancing effect of RF microchannels on skin permeation of arbutin, in vitro skin permeability studies were performed with RF microporation-treated Hartley albino guinea pig skin using Franz diffusion cell system. Furthermore, improved depigmentation ef...