This paper presents a new methodology to solve multi-response statistical optimization problems. This methodology integrates desirability function and simulation approach with a genetic algorithm. The desirability function is responsible for modeling the multi-response statistical problem, the simulation approach generates required input data from a simulated system, and finally the genetic alg...

The aim of this work was to evaluate and optimize formulation of three-layer matrix tablets based on xanthan gum (XG) and sodium alginate for chronotherapeutic pH-independent release of verapamil HCl (VH). Artificial neural networks (ANN) were applied in the optimization and compared with multiple linear regression (MLR). A face-centered central composite experimental design was employed with t...

The purpose of this study is to further examine the relationships among hopelessness, social desirability, and suicidal behavior in the decade-long dispute about the role of social desirability and the ability of the Beck Hopelessness Scale to predict suicidal behavior. Using a stratified random sample of state prison inmates, we found that hopelessness and suicidal behavior remain significantl...

The present study aims to shed some light on an old controversy about the joint impact of acquiescence and social desirability on item responses. There are two main hypotheses: (a) of the two biases, social desirability is by far the prime determinant, and (b) acquiescence operates in all sorts of items, including those impacted by social desirability. A new methodology is harnessed to assess t...

Men's and women's mate preferences impose on each a unique set of adaptive problems that must be solved when judging the desirability of prospective mates. One potentially revealing source of information about an individual's desirability as a romantic partner is contained in the decisions made by same-sex others. The present studies predicted that men's and women's desirability assessments wou...

In this study, response surface methodology was used for optimization of intermittent microwave-convective air drying (IMWC) parameters with employing desirability function. Optimization factors were air temperature (40-80°C), air velocity (1-2 m/sec), pulse ratio) PR ((2-6), and microwave power (200-600 W) while responses were rehydration ratio, bulk density, total phenol content (TPC), color ...