Whether the carcinogenic action of estrogen is an expression solely of its ability to establish and sustain a mammary gland or whether this hormone has in addition to mammary stimulation an independent carcinogenic property per se has been questioned (5). Desoxycortieosterone acetate has been reported to be as effective as estrogen in stimulating the development of mammary glands in young male ...

The author gives an account of his work as post-doc at the University of Geneva in the group of W. Oppolzer, putting emphasis on scientific rigour and ingenuity.

Using the roller tube method of tissue culture, it has been shown that cortisone and compound F inhibit the cytotoxic action of PPD upon macrophages from the splenic tissue of tuberculous guinea pigs. Pretreatment of the cells for 24 hours with hormones before exposure to PPD was found to be essential. Estrone and desoxycorticosterone glucoside had no protective activity. Certain advantages of ...