background: anemia may be considered to be an independent risk factor for the development of diabetic retinopathy (dr) in patients with renal failure. the purpose of this study was to investigate the association between blood hemoglobin level and retinopathy in diabetic patients with normal renal function tests.methods: from 2009 to 2011, 1100 diabetic patients underwent retinal examination. am...

background: few studies regarding oral lesions of children and adolescents were reported in the medical literature. the aim of this study was to determine the frequency of these lesions in patients from birth to 20 years old in babol, northern iran.methods: the slides of all cases of oral lesions in children and adolescents, between 1990 and 2012 were obtained from the pathology archives of sha...

objective: in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. we designed a study for comparing the level of ox-ldl in diabetic patients with macro-albuminuria, micro-albuminuria, versus normo-albuminuric. materials and methods: one hundred and thirty five patients with type 2 diabet...

abstract  introduction: diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. this study was designed to investigate the effect of nigella sativum (ns) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (stz)-induced diabetic rats.  methods: for this p...

background: hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients. the present study was designed to determine the role of gamma amino butyric acid b (gabab) receptor and l-arginine (l-arg) in gaba-induced vasorelaxation in normal and streptozotocin-induced diabetic rat vessels. methods: diabetes was induced by a single i.p. injection of strepto...

introduction: walnut leaf contains large amounts of antioxidants, phenolic compounds and flavonoids and the beneficial effect of these compounds in the treatment of diabetes has been shown. this study investigated the effect of cyclohexane and ethanol extract of walnut leaf on activity of sorbitol dehydrogenase (sdh) enzyme. methods: fifty- six adult male sprague-dawley rats were divided into s...

background: information regarding the frequency and severity of eye involvement in diabetic patients and its risk factors can be useful for prevention and treatment. this study aimed to determine the prevalence of diabetic retinopathy and its associated risk factors in diabetic patients who referred to teaching hospitals in babol, mazandaran.  methods: in this study a total of 1562 patients wit...

considering the anti-diabetic potential of trigonella foenum-graecum (tfg) and its beneficial effect on aortic reactivity of diabetic rats, this study was conducted to evaluate the effect of its alcoholic seed extract on aortic reactivity and also figure out mechanisms including the role of adrenergic and angiotensinergic systems in streptozotocin-diabetic rats. male wistar rats were divided in...

background osteoporosis and chronic kidney disease are common conditions in older adults, and often occur concurrently. bone disease is caused by increased bone turnover accompanying secondary hyperparathyroidism, and by factors such as bone metabolic disorder accompanying kidney disease and postmenopausal or age-related osteoporosis, even in hemodialysis patients. raloxifene is commonly used f...

diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. due to the anti-diabetic and antioxidant activity of pelargonidin (pg), this research study was conducted to evaluate the efficacy of chronic oral pg on alleviating learning and memory disturbance in streptozotocin-diabetic rats. male wistar rats were divided into...