The catalytic asymmetric phospha-Michael reaction of dialkyl phosphine oxides with β,β-disubstituted α,β-unsaturated carbonyl compounds was achieved. The products bearing tetrasubstituted carbon stereocenters were obtained in high yields with excellent enantioselectivities (up to >99% ee).

We report herein the synthesis and characterization of a lutetium dialkyl complex supported by a multidentate, anilido-pyridine-imine ligand and its subsequent transformation into an unprecedented cationic monoalkyl derivative.

α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

Solid-state and solution analysis shows that dialkyl substituents on the central phenyl ring of bis(dioxaborole)s, such as , do not have an appreciable effect on the planarity but do significantly alter the supramolecular assembly of these compounds.

Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives. In that latter particular case, unexpected results have been reported.

Three-component reaction of dialkyl acetylenedicarboxylates, isocyanides and 1,3- diimino isoindoline affords highly functionalized 2,6-dihydropyrimido[2,1-a]isoindole derivatives in good yields under catalyst free and mild reaction conditions.

The Front Cover shows the one-pot procedure for introduction of aminoalkyl chain through dialkyl carbonate chemistry into different phenolic substrates. This green approach is a direct alcohol substitution that avoids use chlorine giving CO2 and ethanol as only reaction by-products. proposed has numerous potential applications N,N-dialkyl ethylamine moieties are incorporated in many pharmacopho...

Some dialkyl alkylphosphonates and dialkyl phenylphosphonates were synthesized by the reactions between trialkyl phosphite and alkyl/aryl halide in the presence of benzene. The synthesized compounds were characterized by elemental analysis, thin layer chromatography (TLC), fourier –transform infrared, ( 1 H, 13 C) nuclear magnetic resonance (NMR) spectroscopic techniques. In vitro fungicidal ac...

Geometrically constrained dioxaphospholane rings were incorporated into a bis(phosphinimine)carbazole ligand (HL) in an effort to generate an ancillary ligand system that is capable of supporting reactive lutetium alkyl functionalities and resistant to cyclometalation reactivity. This new ligand was used to prepare a lutetium dialkyl species, LLu(CH2SiMe3)2; however, the complex exhibited low t...

The synthesis of the title compounds was carried out by reacting dicarboxylic acid chlorides with oximes in the presence of excess triethylamine. Disubstituted malonyl chlorides gave 2-alkenyl-4,4-dialkyl-3,5-isoxazolidinediones (8a-f) and 2,2'-ethylidene-bis[4,4-dialkyl-3,5-isoxazolidinedione]s (9a-f). Compounds 9 were formed from 8 and its N-unsubstituted 3,5-isoxazolidinedione decomposition ...