نتایج جستجو برای: diethyldithiocarbamate
تعداد نتایج: 541 فیلتر نتایج به سال:
The antimycobacterial activities of disulfiram (DSF) and diethyldithiocarbamate (DDC) against multidrug- and extensively drug-resistant tuberculosis (MDR/XDR-TB) clinical isolates were evaluated in vitro. Both DSF and DDC exhibited potent antitubercular activities against 42 clinical isolates of M. tuberculosis, including MDR/XDR-TB strains. Moreover, DSF showed remarkable bactericidal activity...
This study demonstrates a role for superoxide dismutases (Sods) in governing tolerance of Candida albicans biofilms to amphotericin B (AmB). Coincubation of C. albicans biofilms with AmB and the Sod inhibitors N,N'-diethyldithiocarbamate (DDC) or ammonium tetrathiomolybdate (ATM) resulted in reduced viable biofilm cells and increased intracellular reactive oxygen species levels as compared to i...
Brad L. Upham and Kriton K. Hatzios Departm ent of Plant Pathology, Physiology and W eed Science, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA Z. Naturforsch. 41c, 861 — 866 (1986); received April 10/May 20, 1986 Diethyldithiocarbamate, Photoreductant, E lectron D onor, Ascorbate, Superoxide Dismutase Diethyldithiocarbamate (D ED TC ) does not accept elec...
The development of copper-drug complexes (CDCs) is hindered due to their very poor aqueous solubility. Diethyldithiocarbamate (DDC) is the primary metabolite of disulfiram, an approved drug for alcoholism that is being repurposed for cancer. The anticancer activity of DDC is dependent on complexation with copper to form copper bis-diethyldithiocarbamate (Cu(DDC)2), a highly insoluble complex th...
Muscle metabolic by-products during exercise, such as K+, lactic acid, ATP, H+, and phosphate, are well established to be involved in the reflex cardiovascular response to static muscle contraction. However, the role of muscle reactive oxygen species (ROS), a metabolic by-product during muscle contraction, in the exercise pressor reflex (EPR) has not been investigated in detail. In the present ...
In the course of a study of the enzymes of Piricularia oryzae Cav., the fungus causing the blast disease of rice, it was observed that activity of crude polyphenoloxidase preparations from culture filtrates was not inhibited by sodium diethyldithiocarbamate (DEDTC), a widely used inhibitor of copper-containing enzymes. Further investigation revealed that such preparations contained an enzyme wh...
A novel fullerene derivative including a chelating group attached to the fullerene core has been prepared by photoreaction of C60 and sodium diethyldithiocarbamate (NaDDC) in toluene-methanol medium. The optimization of the synthesis procedure was monitored by UV-visible spectroscopy using the spectrum of C60 fullerene as reference; the new material, a C60-NaDDC monoadduct, showed a shoulder at...
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