Objectives: The incidence of differentiated thyroid cancer (DTC) has been increasing rapidly in recent years. Patient age at diagnosis is a good prognostic factor for cancer. DTC the only malignancy that includes as part its staging system. American Joint Committee on Cancer (AJCC) system currently uses 55 years cutoff point. In this study, we aimed to compare clinicopathological features patie...

A significant number of well-differentiated thyroid cancers progress or recur, becoming resistant to current therapeutic options. Mouse models recapitulating the genetic and histological features of advanced thyroid cancer have been an invaluable tool to dissect the mechanisms involved in the progression from indolent, well differentiated tumors to aggressive, poorly differentiated carcinomas, ...