نتایج جستجو برای: digestive system cancer

تعداد نتایج: 3087271  

Journal: :Environmental Health Perspectives 1974
Marvin A. Schneiderman

Human data show a dose-response relationship between industrial exposure to asbestos and later development of cancer of the bronchus and lung and of cancer of the digestive tract. The data do not provide much evidence for a threshold or for the existence of a clearly "safe" level of exposure. Good dose-response data, with quantitative estimates of dose are uncommon; however, in all the literatu...

2017
Kosei Takagi Takahito Yagi Yuzo Umeda Ryuichi Yoshida Daisuke Nobuoka Takashi Kuise Kenjiro Kumano Takeshi Kojima Takuro Fushimi Toshiyoshi Fujiwara

INTRODUCTION Pancreaticoduodenectomy (PD) combined with extended right hemicolectomy (RH) is a challenging procedure for locally advanced malignancies. However, information concerning the reconstruction method of the digestive system is limited. Here, we present a case and surgical technique of a novel intestinal rotation method for digestive reconstruction after PD combined with RH. PRESENTA...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2013
Pan Ke Zhong-De Wu Hua-Song Wen Miao-Xiong Ying Huo-Cheng Long Liu-Guo Qing

Matrix metalloproteinases (MMPs) degrade various components of the extracellular matrix and functional polymorphisms in encoding genes may contribute to genetic susceptibility to many cancers. Up to now, associations between MMP-7 (-181A>G) and digestive system cancer risk have remained inconclusive. To better understand the role of the MMP-7 (-181A>G) genotype in digestive cancer development, ...

2017
Yaohua Tian Zhong Jian Beibei Xu Hui Liu

Comorbidities have considerable effects on survival outcomes. The primary objective of this retrospective study was to examine the association between age-adjusted Charlson comorbidity index (ACCI) score and postoperative in-hospital mortality in patients with digestive system cancer who have undergone surgical resection of their cancers. Using electronic hospitalization summary reports, we ide...

Journal: :The Japanese Journal of Gastroenterological Surgery 1988

2016
Han-Xing Wan Jian-Hong Hu Rei Xie Shi-Ming Yang Hui Dong

Purinergic signaling is important for many biological processes in humans. Purinoceptors P2Y are widely distributed in human digestive system and different subtypes of P2Y receptors mediate different physiological functions from metabolism, proliferation, differentiation to apoptosis etc. The P2Y receptors are essential in many gastrointestinal functions and also involve in the occurrence of so...

Journal: :iranian journal of toxicology 0
سیامک پورعبدیان siamak pourabdian isfahan university of medical sciences, isfahan, iran. نسترن ایزدی مود nastaran eizadi-mood isfahan university of medical sciences, isfahan, iran. پرستو گلشیری parastoo golshiri isfahan university of medical sciences, isfahan, iran. فاطمه امینی fatemeh amini isfahan university of medical sciences, isfahan, iran.

background: hematological effects and digestive and neuro-psychological signs and symptoms are some manifestations of lead toxicity. however, there are conflicting reports of their prevalence among lead exposed workers and their relationship with blood lead levels (bll). this case- control study assessed the relationship between bll and hematological indexes and digestive (abdominal colic, iron...

2018
Ke Wang Yansen Bai Shi Chen Jiao Huang Jing Yuan Weihong Chen Ping Yao Xiaoping Miao Youjie Wang Yuan Liang Xiaomin Zhang Meian He Handong Yang Qingyi Wei Huan Guo Sheng Wei

Although serum tumor biomarkers alpha-fetoprotein (AFP), carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) have been used in digestive cancer risk prediction, the prediction efficiency remains unsatisfactory. The aim of this study was to evaluate whether genetic correction could improve the efficiency of these biomarkers for prediction of digestive cancer risk. We conducted ...

2012
Jing Guo Mingjuan Jin Mingwu Zhang Kun Chen

BACKGROUND MicroRNAs (miRNAs) negatively regulate the gene expression and act as tumor suppressors or oncogenes in oncogenesis. The association between single nucleotide polymorphism (SNP) in miR-196a2 rs11614913 and the susceptibility of digestive system cancers was inconsistent in previous studies. METHODOLOGY/PRINCIPAL FINDINGS An updated meta-analysis based on 15 independent case-control ...

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