نتایج جستجو برای: dimensional culture

تعداد نتایج: 670913  

Journal: :Journal of Visualized Experiments 2013

Journal: :Philosophical Transactions of the Royal Society B: Biological Sciences 2018

Journal: :International Journal of Molecular Sciences 2015

2014
Matthew G. Rubashkin Guanqing Ou Valerie M. Weaver

Cells in vivo exist within the context of a multicellular tissue, where their behavior is governed by homo- and heterotypic cell-cell interactions, the material properties of the extracellular matrix, and the distribution of various soluble and physical factors. Most methods currently used to study and manipulate cellular behavior in vitro, however, sacrifice physiological relevance for experim...

Journal: :Nature nanotechnology 2010
Glauco R Souza Jennifer R Molina Robert M Raphael Michael G Ozawa Daniel J Stark Carly S Levin Lawrence F Bronk Jeyarama S Ananta Jami Mandelin Maria-Magdalena Georgescu James A Bankson Juri G Gelovani T C Killian Wadih Arap Renata Pasqualini

Cell culture is an essential tool in drug discovery, tissue engineering and stem cell research. Conventional tissue culture produces two-dimensional cell growth with gene expression, signalling and morphology that can be different from those found in vivo, and this compromises its clinical relevance. Here, we report a three-dimensional tissue culture based on magnetic levitation of cells in the...

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