Pathology of antibiotic-treated human heart valve allografts. Forty-two human heart valves treated with an antibiotic solution were examined by light and electron micro-scopy up to 168 weeks after grafting in aortic, mitral, and tricuspid positions. There was a progressive degeneration of donor cells and by 40 days both fibroblasts and endothelial cells had vanished, leaving grafts virtually ac...

Introduction Transcatheter valve-in-valve replacement is an attractive alternative to redo open-heart surgery for failing bioprosthetic valves and is increasingly being performed in patients with high surgical risk. Unlike the robust data on aortic valve-in-valve replacement, limited experience with tricuspid valve-in-valve replacement has been reported. Moreover, the feasibility and safety of ...

this paper presents the case of a 35 year-old woman with symptoms of heart failure from the last month. a physical examination at admission showed paleness, dyspnea, peripheral edema and fatigue. in a two-dimensional echocardiography and transesophageal echocardiography, normal thickness but severe left and right ventricular dysfunction with severe pericardial effusion and thickened pericardium...

A rare presentation with rapidly progressive right heart failure due to tricuspid inflow obstruction (simulating right-sided valvular heart disease) caused by a non-coronary cusp sinus of Valsalva aneurysm with small perforation is reported. The aneurysm was causing ball valve obstruction at the tricuspid valve, leading to dilated right atrium and back pressure changes which were relieved after...

The patterns of aortic and tricuspid valve motion in 50 patients with mitral valve prolapse were analyzed by wide-angle, phased-array, two-dimensional echocardiography. Twelve patients (24%) had redundant aortic leaflets bulging into the left ventricular outflow tract during diastole. Eight of 12 patients had aortic regurgitation and seven of 12 had M-mode echocardiographic evidence of aortic v...

Two-dimensional echocardiographic features were correlated with surgical findings in 25 patients with Ebstein's anomaly (age 7 days to 71 years). There was excellent agreement between echocardiographic and surgical findings. Echocardiographic observations of anterior leaflet tethering and restriction of motion, as well as small functional right ventricle, were the strongest noninvasively obtain...

BACKGROUND Tricuspid regurgitation in hypoplastic left heart syndrome has an impact on outcome, but its mechanisms remain unclear. METHODS AND RESULTS Real-time 3-dimensional echocardiography was performed in 35 patients with hypoplastic left heart syndrome (age, 1 month to 10 years; 10 after first-stage Norwood, 12 after superior cavopulmonary shunt, 13 after Fontan). From the 3-dimensional ...

A 66-year-old woman was diagnosed with hepatic metastasized carcinoid tumor of the ileocecal junction resulting in elevated plasma chromogranin A levels and urinary 5-hydroxyindoleacetic acid (5-HIAA) levels. Further examination showed right-sided heart failure with severe tricuspid valve regurgitation. Carcinoid tumors produce serotonin which leads to flushing, secretory diarrhea, bronchospasm...

A vast unmet need exists for tricuspid valve (TV) repair for functional tricuspid regurgitation (FTR) among patients undergoing left heart valve surgery. The FTR is a dynamic entity that is governed by several pathophysiologic mechanisms like TV annular dilatation, annular shape, pulmonary hypertension, left or right ventricle dysfunction, right ventricle geometry, and leaflet tethering. Treatm...

To cite: Miles LF, Leong T, McCall P, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014207732 DESCRIPTION A 41-year-old man presented to an anaesthetic preassessment clinic with a metastatic neuroendocrine tumour and clinical features of carcinoid syndrome for consideration of hepatic resection. He gave a history of worsening exertional dyspnoea and peri...