نتایج جستجو برای: diphtheria toxoid purification and characterization

تعداد نتایج: 16903098  

Journal: :Pediatrics 2015
James D Cherry

In this issue of Pediatrics Acosta et al present a tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis, adsorbed (Tdap) vaccine effectiveness study in adolescents in Washington State during the first 6 months of 2012. Their findings support the previous Tdap effectiveness data from Wisconsin. The duration of Tdap effectiveness is disappointing, particularly because case-control s...

Journal: :PLoS Medicine 2006
Carsten Heilmann Philippe Grandjean Pál Weihe Flemming Nielsen Esben Budtz-Jørgensen

BACKGROUND Developmental exposure to polychlorinated biphenyls (PCBs) has been implicated as a possible cause of deficient immune function in children. This study was designed to assess whether prenatal and postnatal exposure to PCBs impacts on antibody response to childhood immunizations. METHODS AND FINDINGS Two birth cohorts were formed in the Faroe Islands, where exposures vary widely, be...

Journal: :Vaccine 2004
Masanori Isaka Takako Komiya Motohide Takahashi Yoko Yasuda Tooru Taniguchi Yanqiu Zhao Keiko Matano Hideyuki Matsui Jun-Ichi Maeyama Kazunori Morokuma Kunio Ohkuma Norihisa Goto Kunio Tochikubo

Recombinant cholera toxin B subunit (rCTB) which is produced by Bacillus brevis carrying pNU212-CTB acts as a mucosal adjuvant capable of enhancing host immune responses specific to unrelated, mucosally co-administered vaccine antigens. When mice were administered intranasally with diphtheria-pertussis-tetanus (DPT) combination vaccine consisting of diphtheria toxoid (DTd), tetanus toxoid (TTd)...

Journal: :Pediatrics 2017
Roger Baxter Joan Bartlett Bruce Fireman Edwin Lewis Nicola P Klein

BACKGROUND Vaccination against pertussis during pregnancy is recommended to protect newborns, yet there is limited information about the effectiveness of maternal tetanus toxoid, reduced diphtheria toxoid, acellular pertussis (Tdap) vaccine before the first infant dose of diphtheria, tetanus and acellular pertussis (DTaP) vaccine and during the first year of life in infants who have received DT...

Journal: :The Journal of infectious diseases 2000
M Brennan C Vitek P Strebel W Wattigney K Bisgard S Brisgalov V Bragina V Pyanikh M Wharton

During the Russian diphtheria epidemic of the 1990s, adults had an unexpectedly high rate of disease. A retrospective, matched case-control study was done to measure the effectiveness of one, two, or three or more doses of diphtheria toxoid against diphtheria among 40- to 49-year-old Russians. Thirty-nine diphtheria case-patients and 117 controls were studied. Previous vaccinations were include...

Journal: :American journal of kidney diseases : the official journal of the National Kidney Foundation 2001
S Krüger M Müller-Steinhardt H Kirchner B Kreft

Chronic renal failure is associated with a T-cell-dependent immune defect. In the past, various studies have focused on the insufficient immune response to vaccination of hemodialysis patients. An impaired vaccination response rate has been reported for vaccines against hepatitis B, influenza, tetanus, diphtheria, and others. However, no data exist on the long-term success of vaccination agains...

Journal: :Japanese Journal of Medical Science and Biology 1971

Journal: :Pediatrics 2010
Wan-Ting Huang Paul M Gargiullo Karen R Broder Eric S Weintraub John K Iskander Nicola P Klein James M Baggs

OBJECTIVES Receipt of diphtheria-tetanus-whole-cell pertussis vaccine (diphtheria-tetanus toxoids-pertussis [DTP]) is associated with seizures. Limited population-based studies have been conducted on the risk for seizures after receipt of diphtheria-tetanus-acellular pertussis vaccine (diphtheria-tetanus-acellular pertussis [DTaP]). METHODS We conducted a retrospective study from 1997-2006 by...

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