In the present work an attempt has been made to increase the solubility and dissolution rate of lansprozole by formulating it as solid dispersions by lipid carriers such as compritol 888 ATO Phospholipon 90 H and Lipoid S100 by using Fusion method, Kneading method and solvent evaporation method. Further the solid dispersions were compressed as orodispersible tablets by using croscarmelloe sodiu...

We develop a strategy for preparing water-based dispersions of polymer/TiO₂ nanospheres that can be used to form composite materials applicable in various fields. The formed hybrid nanospheres are monodisperse and possess a hierarchical structure. It starts with the primary TiO₂ nanoparticles of about 5 nm, which first assemble to nanoclusters of about 30 nm and then are integrated into monomer...

Solid dispersions have been widely used to enhance the solubility of poorly water soluble drugs. In this study, solid dispersions of valsartan (VAL) with natural polymers such as hupu gum (HG), guar gum (GG) and xanthan gum (XG) were prepared by kneading technique in the weight ratios of 1:1,1:2,1:3 and1:4.The prepared solid dispersions were investigated by X-ray diffraction, infrared spectrosc...

Aim: To enhance the aqueous solubility of olanzapine by using the Solid dispersion technique. Solid dispersions of Olanzapine were prepared by the dispersion method using using PGS and SSG as carriers. Drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. Characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...

The structural and physical stability of solid dispersions have not been adequately explored during spray drying manufacturing processes. In this study a wide range of compositions of naproxen/PVP-VA 64 (poly(1-vinylpyrrolidone-co-vinyl acetate)) and miconazole/PVP-VA 64 solid dispersions prepared by different laboratory spray dryers were collected from various selected locations and used to in...

This paper presents an EM analysis of dispersions & discontinuities in a microstrip transmission lines. Dispersion characteristics of a microstrip lines are investigated by the existing models for study of microstrip lines and then compare the results with Software Simulation. Dispersions on microstrip lines with characteristics impedance 50Ω are investigated for the frequency range 1 to 18 GHz...

Dispersions of isolated single wall carbon nanotubes (SWNTs) in pure organic solvents can usually be prepared only at low concentrations (∼0.01-0.02 g/L). Here, we use poly(vinylpyrrolidone) as a dispersant for unfunctionalized SWNTs in N-methyl-2-pyrrolidone and achieve concentrations of up to ∼0.16 g/L. Such dispersions remain stable by visual inspection for at least 1 year after preparation....

We systematically study the properties of dispersions of iron-based colloids synthesized in a broad size range by thermal decomposition of ironcarbonyl using different stabilizing surfactants. The synthesis results in stable dispersions of monodomain magnetic colloids. Our particles appear to consist of an amorphous Fe(0.75)C(0.25) alloy. Sizes of particles coated with modified polyisobutene or...

In this work, different sizing agent aqueous dispersions based on polyetherimide (PEI) were elaborated in order to improve the interface between carbon fibers and a thermoplastic matrix (PEEK). The dispersions were obtained by the emulsion/solvent evaporation technique. To optimize the stability and the film formation on the fibers, two surfactants were tested at different concentrations, with ...