Various experiments were performed on the limb buds of axolotls to compare the behaviour of amphibian limbs with that previously reported for chick limbs. Following removal of the tip or whole limb bud, extensive powers of regulation were observed since complete limbs always formed. Similarly after distal to proximal grafts intercalary regulation occurred to produce perfect limbs and after prox...

Limb regeneration is a representative phenomenon of organ regeneration in urodele amphibians, such as an axolotl. An amputated limb starts regenerating from a remaining stump (proximal) to lost finger tips (distal). In the present case, proximal-distal (PD) reorganization takes place in a regenerating tissue, called a blastema. It has been a mystery how an induced blastema recognizes its positi...

background: high tibia osteotomy (hto) is a common surgical operation for correction of genu varum deformity. in some patients,there are concurrent tibia vara and genu varum (bow leg). this study aimed to consider the possibility of better correction of bow leg deformity after double level tibial osteotomy (dlto). materials and methods: a case series of 10 patients of genu varum in addition to ...

Canine osteosarcoma is the most commonly diagnosed primary bone tumour in the dog, affecting mainly large and giant breed dogs with the predilection site being the metaphysis of long bones, specifically the distal radius, proximal humerus, distal femur and proximal tibia and fibula. Treatment options are either palliative or curative intent therapy, the latter limb amputation or limb-sparing su...

Objectives- To evaluate the efficacy of platelet rich- plasma (PRP) and plasma rich-growth factor (PRGF®) on the wound healing on distal aspect of horses limbs. Design- Experimental study Animals - Four mixed- breed adult horses, 13 to 21 years of age and weighting 381 ±85 kg Procedures- The Limbs of each horse were treated with PRP, PRGF®, Silver Sulfa diazin and one limb received no treatment...

INTRODUCTION Miyoshi myopathy, a type of distal myopathy with predominant involvement of the posterior calf muscles, has been assigned to mutations in the dysferlin gene. However, many of the late-onset limb-girdle and distal myopathies that resemble dysferlinopathy or Miyoshi myopathy remain unclassified, even after extensive immunohistological and genetic analysis. CASE PRESENTATION We repo...

conclusions the fixator-assisted lengthening plate technique helps to maintain the stability and alignment at both sides of an osteotomy during tibial elongation. it allows the early removal of the external fixator immediately after lengthening is completed. this technique can be applied in children with open physes and in patients with a narrow medullary canal who are unsuitable for limb lengt...

Motor improvements in chronic stroke recovery accrue from coupled protocols of bilateral movements and active neuromuscular stimulation. This experiment investigated coupled protocols and within-limb transfer between distal and proximal joint combinations. The leading question focused on within-limb transfer of coupled protocols on distal joints to a bimanual aiming task that involved proximal ...

QUESTION What is the effect of exercise on reducing impairment and increasing activity in the rehabilitation of people with upper limb fractures? DESIGN Systematic review of controlled trials. PARTICIPANTS Adults following an upper limb fracture. INTERVENTION Any exercise therapy program, including trials where exercise was delivered to both groups providing there was an expectation of di...

The increased variations of temporal gait events when pathology is present are good candidate features for objective diagnostic tests. We hypothesised that the gait events hoof-on/off and stance can be detected accurately and precisely using features from trunk and distal limb-mounted Inertial Measurement Units (IMUs). Four IMUs were mounted on the distal limb and five IMUs were attached to the...