UNLABELLED Distraction osteogenesis is an effective method for lengthening long bones and filling bone defects that result from bone resection. Insufficiency of bone consolidation in the distraction segment is problematic. In this study, we examined whether 3-phase bone scintigraphy can predict the outcome of distraction osteogenesis. We also investigated the effects of chemotherapy and surgica...

Introduction The rate of lengthening has a profound impact on bone formation during distraction osteogenesis. At optimal rates of distraction, palisades of well-vascularized woven bone fill the distraction gap. However, rapid distraction leads to the formation of granulation tissue, fibrocartilage, and cysts, resulting in nonunion. Previous research has demonstrated that rapid rates of distract...

Experimental studies have shown that large corrections of mandibular defects can be done by distraction osteogenesis. Annino et al1 investigated the feasibility of trifocal distraction for the reconstruction of symphyseal defects and they obtained 4.5to 5.5-cm lengthening in canine mandibles by using a rate of 1 mm/day.1 Labbe et al2 used distraction osteogenesis in 5 patients who had gunshot w...

BACKGROUND The aim of this clinical prospective study is to apply and evaluate an approach to reduce the overall orthodontic treatment time, by means of dentoalveolar distraction osteogenesis to achieve rapid canine retraction using an indigenously developed intra-oral tooth-borne distraction device. MATERIALS & METHODS This study was carried out in the Department of Orthodontics and Dentofac...

Congenital brachymetatarsia most commonly involves the fourth ray and may be combined with metacarpal shortening. Now, many reports demonstrated the usefulness of distraction osteogenesis for lengthening of the metatarsals by using an external distraction device. In this article, we treated shortening fourth metatarsal by bone lengthening using the internal distraction device. This technique ha...

Thrombin-related peptide 508 (TP508) accelerates bone regeneration during distraction osteogenesis. Here we examined the effect of TP508 on bone regeneration during distraction osteogenesis by immunolocalization of RUNX2 protein, a marker of osteoblast differentiation, osteopontin (OPN) and bone sialoprotein (BSP), two late markers of the osteoblast lineage. Distraction was performed in tibiae ...

Amputation of the thumb invariably causes marked functional impairment of the hand especially, pinch and grasp functions. In rural areas where highly skilled microvascular surgeries are not available, distraction osteogenesis provides an easy and safe alternative of thumb reconstruction. We report a case of crush injury of the right hand in a 37 year old gentleman in which the right thumb was a...