Background: Differences in the prevalence and impact of hyperhomocytenemia on vascular disease between countries and races have been reported. Most studies have been undertaken in North American and European populations and the importance of plasma total homocysteine (tHcy) level as a risk factor for coronary artery disease in the Middle East particularly in Iran, however, is not known.  Object...

background; brucellosis (malta fever) is a major contagious zoonotic disease, with economic and public health importance. methods; to assess the effect of meteorological (temperature, rainfall, humidity, and wind) and climate parameters on incidence of brucellosis, brucellosis distribution and meteorological zoning maps of zanjan province were prepared using inverse distance weighting (idw) and...

A new test of inheritance, S, is proposed, which uses information from affected as well as unaffected siblings in the fam­ ily. The siblings are analyzed in terms of similarities of haplotypes. The distribution of the proposed S­test is derived under the null hypothesis of random inheritance. Mean and variance are obtained for the distribution. The test is then applied to data sets publ...

background: one third of patients with parkinson’s disease (pd) have mentioned “dysphonia” as their most debilitating communication deficit. patient-based measurements, such as voice handicap index (vhi) add necessary supplementary information to clinical and physiological assessment. there are a few studies about relation between vhi and disease severity in pd, although none of them showed any...

the presence of bejel (endemic syphilis) and its area of distribution in dacht-mieham south-west of iran is demonstrated. the studies of the institute of parasitology and malariology have revealed the presence of disease in few villages of this area witha frequency of 23 to 340/0. the clinical symptoms and epidemiological caracteristics of the disease in iran is described.

Background & Aims: Despite improvements in public health in Iran, cutaneous leishmaniasis has become a growing health issue. About 90% of cutaneous leishmaniasis cases occur in 8 countries including Iran. Kala-azar or visceral leishmaniasis, as an important parasitic disease, is endemic in some areas of Iran. Mapping the distribution of parasitic diseases and determining their relations to geog...

Phenylketonuria (PKU) is the most common autosomal recessive disorder of amino acid metabolism. Thedisease is caused mainly by mutations in the phenylalanine hydroxylase (PAH) gene, encoding phenylalaninehydroxylase (PAH) enzyme. The PAH enzyme deficiency results in the elevation of phenylalanine inthe blood, which may cause severe irreversible mental retardation in the affect...