نتایج جستجو برای: dmpc bilayer

تعداد نتایج: 17902  

2007
Anne S. Ulrich Trevor W. Poile Anthony Watts

Deuterons placed specifically in the head-groups of phospholipids in bilayers were studied by H-NMR, which is a non-perturbing method for directly probing the conformation and dynamics of the deuterated segments at the bilayer surface. Information about the hydrationproperties ofphosphatidvlcholine bilayers was obtained by recording the spin-lattice (T;) relaxation times of DOPC-d. and DMPC-d9 ...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 1990
M Suwalsky M A Espinoza M Bagnara C P Sotomayor

Pentachlorophenol (PCP) is a widely used and highly toxic fungicide. Its toxicity is mainly expressed at the cell membrane level. It is, therefore, of interest to test its ability to alter the lipid bilayer organization. The present study was performed by X-ray diffraction techniques on dimyristoylphosphatidylethanolamine (DMPE) and dimyristoylphosphatidylcholine (DMPC) bilayers and by fluoresc...

Journal: :Langmuir : the ACS journal of surfaces and colloids 2009
Travers H Anderson Younjin Min Kim L Weirich Hongbo Zeng Deborah Fygenson Jacob N Israelachvili

We have investigated the formation of phospholipid bilayers of the neutral (zwitterionic) lipid dimyristoyl-phosphatidylcholine (DMPC) on various glass surfaces from vesicles in various aqueous solutions and temperatures using a number of complementary techniques: the surface forces apparatus (SFA), quartz crystal microbalance (QCM), fluorescence recovery after photobleaching (FRAP), fluorescen...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 1997
M Suwalsky M Benites F Villena F Aguilar C P Sotomayor

Dieldrin is an organochlorine insecticide highly toxic for human beings. Although its exact mechanism of action is not well known, there is evidence that it acts at the cell membrane level. In fact, the lipophilicity of the pesticide as well as that of the phospholipid bilayer present in biological membranes makes the latter a most likely target for the interaction of dieldrin with living organ...

Journal: :Biochimica et biophysica acta 2008
Marilene Alves Barney L Bales Miroslav Peric

The interfacial properties of the negatively charged dimyristoyl-phosphatidylglycerol (DMPG) and the zwitterionic dimyristoyl-phosphatidylcholine (DMPC) vesicles mixed with the fusion inhibitor lysomyristoylphosphatidylcholine (LMPC) are investigated by electron paramagnetic resonance (EPR). At 35 degrees C, addition of 20 mol% of LMPC to the DMPG vesicles increases the effective concentration ...

Journal: :Journal of biomolecular NMR 2015
Matthew T Eddy Yongchao Su Robert Silvers Loren Andreas Lindsay Clark Gerhard Wagner Guido Pintacuda Lyndon Emsley Robert G Griffin

The human voltage dependent anion channel 1 (VDAC) is a 32 kDa β-barrel integral membrane protein that controls the transport of ions across the outer mitochondrial membrane. Despite the determination of VDAC solution and diffraction structures, a structural basis for the mechanism of its function is not yet fully understood. Biophysical studies suggest VDAC requires a lipid bilayer to achieve ...

2016
Ahmad Mehravaran Mahmoud Reza Jaafari Seyed Amir Jalali Ali Khamesipour Reza Ranjbar Mansure Hojatizade Ali Badiee

OBJECTIVES Development of new generation of vaccines against leishmaniasis is possible because long-term protection is usually seen after recovery from cutaneous leishmaniasis. ISCOMATRIX is particulate antigen delivery system composed of antigen, cholesterol, phospholipid and saponin. In this study, the role of ISCOMATRIX bilayer composition made by different phase transition temperature (Tc) ...

Journal: :Biophysical chemistry 2008
Suzana M Andrade Raquel Teixeira Sílvia M B Costa Abílio J F N Sobral

Free base porphyrin (PPhe), derivatized with aminosulfonyl groups linked to the aromatic amino acid phenylalanine at the meso-positions, was mixed with DMPC vesicles. The resulting interaction was studied by absorption, steady-state and transient state fluorescence, at different pHs. At pH=2 to pH=9, the aforementioned porphyrin predominates as an aggregated species, with a co-facial arrangemen...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2011
Martin D Kaye Karin Schmalzl Valeria Conti Nibali Mounir Tarek Maikel C Rheinstädter

From inelastic neutron-scattering experiments and all atom molecular dynamics simulations we present evidence for a low-energy dynamical mode in the fluid phase of a 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine (DMPC) bilayer immersed in a 5% water/ethanol solution. In addition to the well-known phonon that shows a liquidlike dispersion with energies up to 4.5 meV, we observe an additional m...

Journal: :Chemistry and physics of lipids 2015
Suzana Šegota Danijela Vojta Galja Pletikapić Goran Baranović

Infrared (IR) spectroscopy was used to quantify the ion mixture effect of seawater (SW), particularly the contribution of Mg(2+) and Ca(2+) as dominant divalent cations, on the thermotropic phase behaviour of 1,2-dimyristoyl-sn-glycero-3-posphocholine (DMPC) bilayers. The changed character of the main transition at 24 °C from sharp to gradual in films and the 1 °C shift of the main transition t...

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