Homozygosity for a large deletion in the solute carrier family 45, member 2 (SLC45A2) gene causes oculocutaneous albinism (OCA) in the Doberman Pinscher breed. An albino Lhasa Apso did not have this g.27141_31223del (CanFam2) deletion in her SLC45A2 sequence. Therefore, SLC45A2 was investigated in this female Lhasa Apso to search for other possible variants that caused her albinism. The albino ...

Dilated cardiomyopathy (DCM), characterized by chamber dilatation and myocardial systolic and diastolic dysfunction, is one of the most common heart diseases in dogs. The clinical diagnosis is based on findings on echocardiographic and Doppler examinations, with the active exclusion of other acquired or congenital heart diseases. However, the echocardiographic criteria for the diagnosis of DCM ...

To determine the incidence of hepatic diseases in dogs and cats in Japan, a retrospective study was performed using data of 463 canine and 71 feline liver biopsies at the Veterinary Medical Center of the University of Tokyo. The most common canine hepatic disease was microvascular dysplasia (MVD) and occupied 29.4% of all diagnoses. This terminology might contain "real" MVD and primary portal v...

The Belgian Malinois (BM) is an excellent working dog that typically shows a circling behavior when placed in a confined space. Moreover, individuals showing moderate running in circles (one kind of obsessive compulsive behavior) in confined spaces typically show better work performance compared to those without the circling behavior or to those with a serious circling behavior (which can be de...

Pathogenesis Hoerlein determined that intervertebral disc disease (IVDD) accounted for 2.02% of all diseases diagnosed in dogs (Hoerlein 1952). Incidence of IVDD peaks at 4 to 6 years of age in chondrodystrophic breeds and at 6 to 8 years in nonchondrodystrophic breeds (Priester 1976). The Dachshund had the highest frequency followed in succession by the Pekingese, Welsh corgi, Beagle, Lhasa Ap...

Objective. To establish signalment and phenomenology of canine idiopathic head tremor syndrome (IHTS), an episodic head movement disorder of undetermined pathogenesis. Design. Retrospective case series. Animals. 291 dogs with IHTS diagnosed between 1999 and 2013. Procedures. Clinical information was obtained from an online community of veterinary information aggregation and exchange (Veterinary...

BACKGROUND The most accepted means of evaluating the response of a patient with cervical spondylomyelopathy (CSM) to treatment is subjective and based on the owner and clinician's perception of the gait. OBJECTIVE To establish and compare kinetic parameters based on force plate gait analysis between normal and CSM-affected Dobermans. ANIMALS Nineteen Doberman Pinschers: 10 clinically normal...

A Espondilomielopatia cervical ou Síndrome de Wobbler se caracteriza por compressões dinâmicas e estáticas da medula espinhal das raízes nervosas que causam sinais neurológicos musculares, mais comumente a dor cervical. O presente estudo teve como discorrer sobre etiologia, diagnóstico, sintomas, fisiopatologia, tratamento prognóstico espondilomielopatia em cães. Google Acadêmica, PubMed livros...