INTRODUCTION In donor health research, the 'Healthy Donor Effect' (HDE) often biases study results and hampers their interpretation. This refers to the fact that donors are a selected 'healthier' subset of a population due to both donor selection procedures and self-selection. Donors with long versus short donor careers, or with high versus low donation intensities are often compared to avoid t...

Abstract Implementation of access to donate post mortem tissue among pediatric brain tumor patients remains a challenge[DSM1] . Previous attempts develop post-mortem network have been jeopardized by barriers such as lack education, logistical coordination donation, and difficulties effectively communicating the benefit donations families. [CC2] Utilizing feedback from patients’ families, clinic...

monetary compensation for human eggs used in research is a controversial issue and raises major concerns about women’s health and rights, including the potential of exploitation and undue inducement. human eggs are needed for various types of studies and without payment, it would be impossible to procure sufficient eggs for vital research. therefore, a solution seems necessary to prevent exploi...

This article reports the results of an exploratory study on corporate philanthropy using a sample of 206 Canadian companies. The results show that a corporation is more likely to have a professional donation program if it is large, privately owned, and the manager of the corporation acts as a volunteer fundraiser for a charitable organization. The second part of the study finds that the level o...

BACKGROUND Upper age limits for blood donors are intended to protect elderly blood donors from donor reactions. However, due to a lack of data about adverse reactions in elderly blood donors, upper age limits are arbitrary and vary considerably between different countries. METHODS Here we present data from 171,231 voluntary repeat whole blood donors beyond the age of 68 years. RESULTS Blood...

BACKGROUND Shortfalls in deceased organ donation lead to shortages of solid organs available for transplantation. We assessed rates of deceased organ donation and compared hospitals that had clinical services for transplant recipients (transplant hospitals) to those that did not (general hospitals). METHODS We conducted a population-based cohort analysis involving patients who died from traum...

BACKGROUND The iron hypothesis suggests that females are protected from atherosclerosis by having lower iron stores than men, thus limiting oxidation of lipids. OBJECTIVE To test the iron hypothesis by comparing cardiovascular event rates in whole blood donors compared with nondonors. DESIGN Prospective cohort with telephone survey follow up. SETTING The State of Nebraska, USA. PARTICIP...

This is a questionnaire based study of 501 women enquiring about anonymous oocyte donation at a private in-vitro fertilization (IVF) unit, investigating the demographic characteristics and logistic issues involved in ovum donation. The 501 women were made up of 356 women who did not donate ('non-donors') and 145 women who eventually donated their oocytes ('donors'). Although there was a majorit...

Growing incidence of end-stage renal disease, shortage of kidneys from deceased donors and a better outcome for recipients of kidneys from living donor have led many centres worldwide to favour living donor kidney transplantation programmes. Although criteria for living donation have greatly evolved in recent years with acceptance of related and unrelated donors, an immunological incompatibilit...