The metallic fixations used in surgical procedures to support the spine mechani-cally usually consist of high-density materials. Radiation therapy to palliate spinal cord compression can include prophylactic inclusion of potential tumor around the site of such fixation devices. Determination of the correct density and shape of the spine fixation device has a direct effect on the dose calculatio...

PURPOSE The genes for cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) have been identified as important genetic determinants of warfarin dosing and have been studied. We developed warfarin algorithm for Korean patients with stroke and compared the accuracy of warfarin dose prediction algorithms based on the pharmacogenetics. MATERIALS AND METHODS A tota...

clustering is one of the known techniques in the field of data mining where data with similar properties is within the set of categories. k-means algorithm is one the simplest clustering algorithms which have disadvantages sensitive to initial values of the clusters and converging to the local optimum. in recent years, several algorithms are provided based on evolutionary algorithms for cluster...

We analyze the stability and convergence of first-order accurate and second-order accurate timestepping schemes for the Navier-Stokes equations with variable viscosity. These schemes are characterized by a mixed implicit/explicit treatment of the viscous term, in which a numerical parameter, λ, determines the degree of splitting between the implicit and explicit contributions. The reason for th...

BACKGROUND The study summarised in this report aimed to investigate the interplay between fluence complexity, dose calculation algorithms, dose calculation spatial resolution and delivery characteristics (monitor units, effective field width and dose delivery against dose prediction agreement) was investigated. A sample set of complex planning cases was selected and tested using a commercial tr...

Background: Total Body Irradiation (TBI) is different from standard radiotherapy in many aspects, so it is not easy to predict the delivered dose to the patient under TBI treatment. Diode dosimetry procedures for surface dose reading can help to define variations of the actually delivered dose from the prescribed one. The aim of this study was to describe the measurements made to calib...

Introduction: Radiotherapy is an effective modality to treat esophageal carcinoma. Due to various inhomogenous tissues with a variety of physical and radiological properties which can cause uncertainty in accurate dose calculations in radiation therapy, accuracy of TPS is very important. The aim of this study was to quantify dose calculation accuracy of CoreplanTM TPS in an inh...