BACKGROUND Radiation-related lymphopenia has been associated with poor patient outcome. Our aim was to identify predictors of lymphopenia after palliative radiotherapy, with a focus on dose-volume parameters. PATIENTS AND METHODS To retrospectively assess patients with various cancers who had undergone palliative radiotherapy, we delineated three organs at risk: the volume enclosed by the bod...

BACKGROUND Inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery. OBJECTIVE In the present study, the performance of five algorithms via Monte Carlo, Pencil Beam, Convolution, Fast Superposition and Superposition were evaluated in lung cancer Intensity Modulated Radiotherapy planni...

cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. however, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    the purpose of this study was to determine the extent of change in...

background: we aimed to compare field-in-field technique (fif) with conformal tangential field radiotherapy (crt) in terms of dosimetric benefits for early stage breast cancer radiotherapy. materials and methods: twenty consecutive left-side breast cancer patients who underwent breast-conserving surgery were included to the study. for each patient, two different treatment plans were created for...

To determine predictive factors for temporal lobe injury (TLI) in nasopharyngeal carcinoma patient (NPC) treated with intensity-modulated radiation therapy (IMRT). A total of 695 NPC cases treated with IMRT were retrospectively analyzed. TLI was diagnosed on MRI images. Volume-dose histograms for 870 evaluable temporal lobes were analyzed, and the predictive factors for the occurrence of TLI wa...

introduction: average glandular dose calculation in mammography with mo-rh target-filter and dose calculation for different situations is accurate and fast. material and methods: in this research, first of all, x-ray spectra of a mo target bombarded by a 28 kev electron beam with and without a rh filter were calculated using the mcnp code. then, we used the sobol-wu parameters to write a fortra...

We propose a comparative dosimetric study of whole-breast hypofractionated radiation therapy using helical tomotherapy (HT) in supine position and 3-D conformal radiotherapy (3D-CRT) in prone position. Twelve patients undergoing breast-conserving therapy were retrospectively selected from October to December 2012. Specific dose-volume parameters were selected for the study. The target coverage ...