A simple real-time beam tuning program has been developed for use at the KEK B-Factory injector linac. The program features the ability to adjust an arbitrary combination of parameters (e.g. magnet currents and RF phases) in order to optimize an arbitrary combination of monitor values (e.g. the ratio of a downstream beam current to gun current). Based on the downhill-simplex method[2][?], it re...

A gradient free optimization-simulationmethod for processesmodelledwith the simulator AspenHYSYS is developed. The tool is based on a Tabu Search (TS) and the Nelder-Mead Downhill Simplex (NMDS) method. The local optima that result from the TS are fine-tuned with NMDS to reduce the required number of simulations. The tool has been applied to find the total refrigerant flow rate, composition and...

Recognition of specific functionally-important DNA sequence fragments is considered one of the most important problems in bioinformatics. One type of such fragments are promoters, i.e., short regulatory DNA sequences located upstream of a gene. Detection of promoters in DNA sequences is important for successful gene prediction. In this paper, Support Vector Machine (SVM) is used for classificat...

The thermal and optical properties of multilayered dental tissue structure, the result of the surface-grown prismless layer on enamel, were evaluated simultaneously using multiparameter fits of photothermal radiometry frequency responses. The photothermal field generated in a tooth sample with near-infrared laser excitation was described using a coupled diffuse-photon-density and thermal wave m...

Downhill running is associated with fiber damage, inflammation, delayed-onset muscle soreness, and various functional deficits. Curcumin, a constituent of the Indian spice turmeric has been investigated for its anti-inflammatory activity and may offset some of the damage and functional deficits associated with downhill running. This study examined the effects of curcumin on inflammation and rec...

A path π = (v1, v2, . . . , vk+1) in a graph G = (V,E) is a downhill path if for every i, 1 ≤ i ≤ k, deg(vi) ≥ deg(vi+1), where deg(vi) denotes the degree of vertex vi ∈ V. The downhill domination number equals the minimum cardinality of a set S ⊆ V having the property that every vertex v ∈ V lies on a downhill path originating from some vertex in S. We investigate downhill domination numbers o...

BioPSE is a scientific programming environment that allows the interactive construction, debugging, and steering of large-scale scientific computations. BioPSE can be envisioned as a “computational workbench,” in which a scientist can design and modify simulations interactively via a dataflow programming model. As opposed to the typical “off-line” simulation mode (in which the scientist manuall...

We develop a method and a computer code for the systematic optimization of a transferable tight-binding model for carbon-hydrogen compounds. We take as reference a density-functional theory calculation in the local density approximation and, using a «downhill simplex» routine, we minimize the squared difference between the energies predicted by the reference model and those obtained with our ti...

We present an approach for registering an aerial Digital Elevation Model (DEM) with a color intensity image obtained using a camera mounted on a mobile robot. An approximate measurement of the camera pose is obtained using auxiliary sensors on-board the robot. The DEM is transformed into a depth map in the camera’s coordinate system using this initial pose. The problem is now simplified to the ...

The immense development rate of wireless technologies has also brought new requirements for the RF design of transmitters. The design challenge is to optimize multiband devices with minimal dimensions and weight as well as an appealing appearance, which nevertheless operate well within varyingly complex environments such as frequently changing positions within the closest vicinity of the human ...