Background: Overdoses with cardiovascular drugs are related with significant morbidity and mortality. Beta-adrenergic blockers, calcium-channel blockers (CCBs), thiazide, digoxin and angiotensin converting enzyme (ACE) inhibitors represent five of the most important classes of cardiovascular drugs. Overdoses with cardiovascular drugs are typically caused by exploratory ingestion by children or ...

A case of digoxin poisoning following the co-administration of digoxin and clarithromycin in a 28 year old male is described. Since the aetiology of chronic digoxin poisoning is often unclear, clinicians should be aware of the potential drug-drug interaction between digoxin and clarithromycin.

The elderly are particularly vulnerable to drug-induced morbidity. They may suffer from multiple medical problems leading to long-term drug use. Polypharmacy together with ageing-related changes in pharmacokinetics, pharmacodynamics and homeostatic mechanisms increases the risk of adverse drug reactions. Drug-related problems (adverse drug reactions, therapeutic failure and poisoning) are impor...

there is inadequate knowledge about acute poisoning as a common problem in children. acute poisoning in children, , is one of the health problems, requiring immediate treatment. case report: a two-month-old male infant with discoloration of the nails was admitted to the emergency pediatric unit of imam reza hospital, mashhad, iran in 2014. following clinical evaluations, the blood lead level wa...

background: profile of acute poisonings varies from country to country depending on the ease of availability of substances and socio-economic condition of people; however, very little information from the united arab emirates (uae) have been published, so far. this study was designed to find out the most common causes of overdose and poisoning in patients admitted to the emergency department of...

background: a good proportion of poisoned patients treated at poisoning wards are elderly. this study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in hamadan, western iran. methods: in this retrospective cross-sectional study, poisoned patients aged 60 years and older treated at department of poisoning of farshchian hospital from march 2008 to march 2013 were...

Background: A good proportion of poisoned patients treated at poisoning wards are elderly. This study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in Hamadan, western Iran. Methods: In this retrospective cross-sectional study, poisoned patients aged 60 years and older treated at department of poisoning of Farshchian Hospital from March 2008 to March 2013 wer...

INTRODUCTION Paracetamol is one of the most commonly used analgesics and antipyretics available without limits as preparations of the OTC group (over the counter drugs). Overdose and poisoning with this drug always brings about the risk of acute hepatic failure. The objective of the study was a retrospective evaluation of patients hospitalized in the Paediatric Clinic during the period 2004-201...

Intensivists are confronted with poisoned patients on a routine basis, with clinical scenarios ranging from known drug overdose or toxic exposure, illicit drug use, suicide attempt, or accidental exposure. In addition, drug toxicity can also manifest in hospitalized patients from inappropriate dosing and drug interactions. In this review article, we describe the epidemiology of poisoning in the...