نتایج جستجو برای: drug resistancsequence homology
تعداد نتایج: 635775 فیلتر نتایج به سال:
SARS-CoV-2 PLpro was investigated as a therapeutic target for potent antiviral drugs due to its essential role in not only viral replication but also regulating the inborn immune response. Several computational approaches, including homology modelling, molecular docking, and dynamics (MD) studies, were employed search promising treating SARS-CoV-2. Eighty-one compounds, sub-structurally similar...
Endophytic bacteria are sized microorganisms found in plant tissues that known to produce secondary metabolites, one of which is the ?-amylase inhibitor. Plant potential closely related endophytic present tissues. The study aimed determine rubber plants inhibitors and identify molecular using 16S rRNA gene sequence. isolates used were L1M1.A2, L1M1.B4, L2M1.A27. activity inhibitor was tested by...
Motivation: Owing to its importance in both basic research (such as molecular evolution and protein attribute prediction) and practical application (such as timely modeling the 3D structures of proteins targeted for drug development), protein remote homology detection has attracted a great deal of interest. It is intriguing to note that the profilebased approach is promising and holds high pote...
Background: Swine flu has become a life-threatening disease involving two main proteins neuraminidase (NA) and hemagglutinin (HA). Inhibition of NA, the protein responsible for initiation viral infection is important treatment step in eradication swine flu. In silico analysis natural compounds serves as lead drug development. Objective: The aim this study to obtain 3 dimensional structure (HIN1...
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