Reopening of the ductus arteriosus after successful indomethacin-induced closure has become a major problem with indomethacin treatment. In full-term human newborns and lambs, the ductus behaves like ischemic tissue after its initial constriction. Its ability to continue to relax or contract depends on the amount of left-to-right shunt through the ductus lumen. To see if ductus constriction in ...

An aneurysm of the ductus arteriosus is a rare finding, particularly in the adult population. These saccular aneurysms arise at the site of an incompletely obliterated ductus arteriosus along the lesser curvature of the aortic arch. Left untreated, it is associated with a high risk of potentially life-threatening complications including rupture, infection and thromboembolism. As a result, surgi...

Right aortic arch with isolation of the left subclavian artery is a rare anomaly. The incidence of bilateral ductus arteriosus is sporadic, and a right aortic arch with isolation of the left subclavian artery in association with bilateral ductus arteriosus is therefore extremely rare. Since the symptoms and signs of isolation of the left subclavian artery can include the absence or underdevelop...

[1] Shim D, Fedderly RT, Beekman III RH, Ludomirsky A, Young ML, Schork MA, Lloyd TR. Follow-up of coil occlusion of patent ductus arteriosus. J Am Coll Cardiol 1996; 28. 207-11. [2] Galal O, de Moor M, Fadley F et al. Problems encountered during introduction of Gianturco coils for transcatheter occlusion of the patent arterial duct. Eur Heart J 1997; 18: 625-30. [3] Sommer RJ, Gutierrez A, Lai...

Patent ductus arteriosus (PDA) is the most prevalent cardiovascular defect and is more often seen in females; premature babies are at increased risk. For both sexes, a relationship exists between the risk of this defect occurring and the higher dimensions of the ductus arteriosus. In this study, we examined the relationship between the dimensions of the ductus arteriosus (diameter, length, capa...

Patent ductus arteriosus (PDA) is a persistent patency of a vessel normally present in the fetus that connects the pulmonary arterial system to the aorta. The ductus arteriosus fails to close at birth when breathing commences and placental blood circulation is removed. Closure of the ductus arteriosus arises in response to decline pulmonary vascular resistance and increased systemic vascular re...

Isolation of the left common carotid or left innominate artery from the aortic arch is rare. A six week malformed infant with a right aortic arch had isolation of a left innominate artery and connection to the pulmonary artery by a left ductus arteriosus. A right ductus arteriosus had been ligated. Another infant with a right aortic arch and ostium primum atrial septal defect was shown to have ...

There are very few reports on successful management of young children with coexistence of two congenital heart defects, coarctation of aorta and patent ductus arteriosus. These lesions can be treated either simultaneously or sequentially. Herein, we present the first successful report of simultaneous balloon angioplasty and Amplatzer duct occluder device implantation in a single-sitting in an 8...

The risk of developing infective endocarditis in relation to a pre-existing cardiac lesion varies according to the lesion. In persistent ductus arteriosus it is approximately one in every 300 patient-years. Assuming a 70 year life a patient with persistent ductus arteriosus has a 20% risk of developing infective endocarditis. After surgical closure it is presumed that this risk declines to that...

Patent ductus arteriosus (PDA) is a congenital disorder in heart, wherein the ductus arteriosus fails to close after birth. This leads to the generation of a left-to-right shunt, leading to pulmonary hypertension. Color Doppler echocardiography is essential for the diagnosis. The identification of a diastolic flow oriented in the opposite direction in the pulmonary artery finalizes the diagnosi...