BACKGROUND Evidence-based practice (EBP) is an essential skill and ethical obligation for all practicing health professions clinicians because of its strong association with improved health outcomes. Emerging evidence suggests that faculty who prepare these clinicians lack proficiency to teach EBP. OBJECTIVES The purpose of this study was to describe; 1) health profession faculty beliefs abou...

CONTEXT Evidence-based practice (EBP) is the integration of the best research evidence with patients' values and clinical circumstances in clinical decision making. Teaching of EBP should be evaluated and guided by evidence of its own effectiveness. OBJECTIVE To appraise, summarize, and describe currently available EBP teaching evaluation instruments. DATA SOURCES AND STUDY SELECTION We sea...

Purpose: Evidence-based practice (EBP) integrates the best evidence from research, clinician expertise, and patient preferences values to deliver highest quality of care improve outcomes. Occupational therapy (OT), physical (PT), rehabilitation students gain exposure EBP through both didactic experiential learning. The differences in cultural, educational systems, student learning styles betwee...

Recent studies have shown that two CAAT/enhancer binding protein (C/EBP) sitesare critically important for efŽcient human immunodeŽciencyvirus (HIV) type 1 (HIV-1) replication within cells of the monocyte/macrophage lineage, a primary cell type infected by HIV-1 and a potentially important vehicle for transport of virus to the central nervous system (CNS). Given the relevance of HIV-1 LTR seque...

BACKGROUND Multihospital healthcare system leaders and individual nurses are challenged to integrate standardized evidence-based practices that support continuous performance improvement in their systems. AIM This study was undertaken to evaluate the strength of and the opportunities for implementing evidence-based nursing practice across a diverse 9-hospital system located in the mid-Atlanti...

CCAAT enhancer-binding protein (C EBP) , C EBP , and peroxisome proliferator activated receptor (PPAR) act in a cascade where C EBP activates expression of C EBP and PPAR , which then function as pleiotropic activators of genes that produce the adipocyte phenotype. When growth-arrested 3T3-L1 preadipocytes are induced to differentiate, C EBP is rapidly expressed but still lacks DNA-binding acti...

The CCAAT enhancer binding protein alpha (C/EBP alpha) transcription factor plays a critical role in granulocytopoiesis. Mice with a disruption of the C/EBP alpha gene demonstrate an early block in granulocytic differentiation, and disruption of C/EBP alpha function is a common theme in many types of human acute myelogenous leukemia, which is characterized by a block in myeloid development. To ...

Wei W, Yang H, Menconi M, Cao P, Chamberlain CE, Hasselgren P-O. Treatment of cultured myotubes with the proteasome inhibitor -lactone increases the expression of the transcription factor C/EBP . Am J Physiol Cell Physiol 292: C216–C226, 2007. First published September 20, 2006; doi:10.1152/ajpcell.00282.2006.— The role of the proteasome in the regulation of cellular levels of the transcription...

Background and aims: The pace of change in the delivery of health care along with professional responsibilities of clinical staff to provide high quality services, wants to the necessity of incorporating of research evidence in decision-making. Implementation of EBP has positive implications for clinical staff, patients, and organizations. Implementation of EBP in clinical settings is a long-te...

The transcription factor, CCAAT/enhancer binding protein (C/ EBP ) is important in the terminal differentiation of granulocytes, hepatocytes, and adipocytes, and recurrent mutations of C/EBP were described in acute myeloid leukemia. In the lung, C/EBP is expressed in bronchial cells and type II pneumocytes. Abnormal proliferation of the latter cell type was reported in C/EBP knockout mice. We d...