Post-transcriptional editing of pre-mRNAs through the action of dsRNA adenosine deaminases results in the modification of particular adenosine (A) residues to inosine (I), which can alter the coding potential of the modified transcripts. We describe here three sites in the para transcript, which encodes the major voltage-activated Na(+) channel polypeptide in Drosophila, where RNA editing occur...

Trypanosoma brucei has three distinct approximately 20S editosomes that catalyze RNA editing by the insertion and deletion of uridylates. Editosomes with the KREN1 or KREN2 RNase III type endonucleases specifically cleave deletion and insertion editing site substrates, respectively. We report here that editosomes with KREPB2, which also has an RNase III motif, specifically cleave cytochrome oxi...

RNA editing is the post-transcriptional conversion from C to U before translation, providing a unique feature in the regulation of gene expression. Here, we used a robust and efficient method based on RNA-seq from non-ribosomal total RNA to simultaneously measure chloroplast-gene expression and RNA editing efficiency in the Greater Duckweed, Spirodela polyrhiza, a species that provides a new re...

Adenosine-to-inosine (A-to-I) RNA editing, catalysed by ADAR enzymes conserved in metazoans, plays an important role in neurological functions. Although the fine-tuning mechanism provided by A-to-I RNA editing is important, the underlying rules governing ADAR substrate recognition are not well understood. We apply a quantitative trait loci (QTL) mapping approach to identify genetic variants ass...

the purpose of the present study is to develop appropriate scoring scales for each of the defined stages of the writing process, and also to determine to what extent these scoring scales can reliably and validly assess the performances of efl learners in an academic writing task. two hundred and two students’ writing samples were collected after a step-by-step process oriented essay writing ins...

This paper presents a novel approach to multiresolution editing of a triangular mesh. The basic idea is to embed an editing area of a mesh onto a 2D rectangle and interpolate the user-specified editing information over the 2D rectangle. The result of the interpolation is mapped back to the editing area and then used to update the mesh. We adopt harmonic maps for the embedding and multilevel B-s...