Abstract This review describes the basic principles of radiometal-theranostics and its dawn based on development positron-emitting 86 Y Y-labeled radiopharmaceuticals to quantify biodistribution dosimetry 90 analogue therapeutics. The nuclear inorganic (including cross section data, irradiation, radiochemical separation recovery) led preclinical clinical evaluation citrate EDTMP complexes yield...

BACKGROUND Systemic therapy with radionuclides may be used for the treatment of patients with painful skeletal metastases owing to its efficacy, low cost and low toxicity. Imported radionuclides for pain palliation, like Strontium-89 are expensive; particularly for developing countries. In the Indian scenario, Samarium-153 (Sm-153) is produced in our own reactors and as a result, it is readily ...