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INTRODUCTION .......................................................................... DNA SUPERCOILING AND TOPOISOMERASES ............................................. CONTROL OF TOPOISOMERASE GENE EXPRESSION ...................................... ROLE OF TOPOISOMERASES AND SUPERCOILING IN DNA REPLICATION................. Elongation Phase of Replication ..........................................

1 Department of Electrical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang 790-784, Korea; [email protected] (D.K.); [email protected] (M.P.) 2 Department of Creative IT Excellence Engineering and Future IT Innovation Laboratory, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang 790-784, Korea; [email protected] * Corres...