The Ehrlich ascites carcinoma of mice, first described by Loewenthal and Jahn (26), has in recent years been the subject of a great many investigations. Klein et cd. have studied certain of the biological properties and the nucleic acid con tent of this tumor (15, 17), and Christensen and co-workers (7, 8) have inquired into the capacity of the tumor to concentrate amino acids. Moldave (33) has...

Ehrlich ascitic carcinoma, as developed in albino mice, has been used as a source of hemagglutinating and complement-fixing antigens, and it proved to be suitable for one type of antigen, or both, for at least 12 viruses of 16 tested. Hemagglutinins were obtained with members of arbovirus groups A, B, and C; complement-fixing antigens were obtained for at least one member of each antigenic grou...

The Ehrlich mouse ascites tumor has become one of the widely used experimental cancers, par ticularly, as pointed out by Klein (6), in those studies dealing with quantitative aspects of tu mor biology. This tumor has been studied exten sively by a number of previous investigators. Loewenthal and Jahn (11) found that intraperitoneal inoculation with organ brei containing the Ehrlich carcinoma pr...

Spirulina is a blue-green alga used as a dietary supplement. It has been shown to possess anti-inflammatory, antioxidant, and hepatoprotective properties. This study was designed to evaluate the antitumor effect of spirulina (200 and 800 mg/kg) against a murine model of solid Ehrlich carcinoma compared to a standard chemotherapeutic drug, 5-fluorouracil (20 mg/kg). Untreated mice developed a pa...

The antitumor activity of 2,3-dihydroxybutyraldehyde on Ehrlich carcinoma, Sarcoma 180, and Yoshida AH 130 hepatoma, as well as the aldehyde dehydrogenase activity in these tumors, was studied. 2,3-Dihydroxybutyraldehyde at nontoxic doses (500 mg/kg body weight i.p. daily for 7 days) slowed down the growth of solid and ascites tumors in mice. The treatment completely prevented the development o...

Results from in vivo and from serum-free primary cultures of Ehrlich cells suggest that the expression of mitogen-regulated protein/proliferin (MRP/PLF) mRNAs is not essential for proliferation of this murine tumor. Two sizes for MRP/PRL-related open reading frames (ORFs) have been detected by reverse transcription/PCR amplification. They are almost identical to that reported for PLF-1; but 20%...