In order to develop a new skin whitening agent, safflower (Carthamus tinctorius L.) seeds were evaluated for melanogenesis inhibitory activity and its active principles were identified following activity-guided isolation. The 80% aqueous methanol extract and ethyl acetate fraction from safflower seeds showed a significant inhibition for mushroom tyrosinase. Three active compounds, N-feruloylser...

In the present study we investigated the comparative genotoxic potential of laser rays and gamma rays on somatic and gametic cells of safflower (Carthamus tinctorius L.). Mutagenic parameters like mitotic and meiotic consequences were accessed from the plants that showed a linear relationship between dose absorbed and chromosomal anomalies. A wide spectrum of chromosomal aberrations was encount...

In this research, our aim was to determine the effects of gibberellic acid, which was applied to safflower plants (Carthamus tinctorius L. cv. Dinçer 5-118) for pollen sterility induction, on some physiological activity and endogenous hormone levels of the seeds. Exogenously applied gibberellic acid (GA3) strongly influenced the endogenous hormone levels of the seeds by decreasing the levels of...

Accurate assembly of complete genomes is facilitated by very high density genetic maps. We performed low-coverage, whole-genome shotgun sequencing on 96 F6 recombinant inbred lines (RILs) of a cross between safflower (Carthamus tinctorius L.) and its wild progenitor (C. palaestinus Eig). We also produced a draft genome assembly of C. tinctorius covering 866 million bp (∼two-thirds) of the expec...

Safflower (Carthamus tinctorius L.) is an oil-crop suitable for semi-arid agriculture, but its physiological response to agronomic inputs has yet to be fully evaluated. The effect of fertiliser on the physiology and production of Safflower grown in pots filled with standard grade perlite inside a semi-controlled glass house was studied. Plants were initially irrigated with 20-100 ml standard hy...

Drought is a main stressor affecting plant production worldwide. Safflower (Carthamus tinctorius L.) known to exploit biochemical strategies tolerate drought stress. However, the little so far about these does not guarantee safflower yield stability in future. To fill gap, changes traits and antioxidant activities of were monitored using 100 genotypes under two non-stress drought-stress field c...

BACKGROUND Carthamus tinctorius L. (Compositae) has been used in Iranian traditional medicine for treatment of diabetes. In this study, anti-diabetic effect of its hydroalcoholic extract was compared with that of glibenclamide. METHODS MALE WHITE WISTAR RATS WERE RANDOMLY ALLOCATED INTO FOUR GROUPS OF SIX EACH: nondiabetic control; diabetic control; diabetic treated with hydroalcoholic extrac...