Microfabricated impedance cytometers have been developed to measure the electrical impedance of single biological particles at high speed. A general approach to analytically solve the electric field distributions for two different designs of cytometers: parallel facing electrodes and coplanar electrodes, using the Schwarz-Christoffel Mapping method is presented. Compared to previous analytical ...

In disease prophylaxis, single cell inspection provides more detailed data compared to conventional examinations. At the individual cell level, the electrical properties of the cell are helpful for understanding the effects of cellular behavior. The electric field distribution affects the results of single cell impedance measurements whereas the electrode geometry affects the electric field dis...

Abstrac t Electroporation or electropermeabilization is a phenomenon observed when lipid bilayers, generally cell membranes, are exposed to high electric field pulses becoming transiently permeable to molecules that under regular conditions are not able to penetrate through them. This change in molecular permeability is believed to be produced by transient aqueous pores created in the lipidic s...

Dictyostelium discoideum cells respond to periodic signals of extracellular cAMP by collective changes of cell-cell and cell-substrate contacts. This was confirmed by dielectric analysis employing electric cell-substrate impedance sensing (ECIS) and impedance measurements involving cell-filled micro channels in conjunction with optical microscopy providing a comprehensive picture of chemotaxis ...

A quantitative theory of the middle-ear acoustics i developed and expressed interms of an electric analog. The analog network is based on the functional anatomy of the middle ear. The numerical values of its elements are derived from impedance measurements on normal and pathological ears and from anatomical data. It is shown that the input impedance of the analog agrees within the experimental ...

The electrochemical impedance of an iron electrode often shows the capacitive and inductive loops on the complex plane. The capacitive loop originates from the time constant of the charge transfer resistance and the electric double layer capacitance. The inductive loop is explained by Faradaic processes involving the reaction intermediate. In some cases, these loops deviate from a true semicirc...

To combine insights obtained from electric field potentials (LFPs) and neuronal spiking activity (MUA) we need a better understanding of the relative spatial summation of these indices of neuronal activity. Compared to MUA, the LFP has greater spatial coherence, resulting in lower spatial specificity and lower stimulus selectivity. A differential propagation of low- and high-frequency electric ...

An impedance-based temperature estimation method is investigated considering the electrochemical non-equilibrium with short-term relaxation time for facilitating the vehicular application. Generally, sufficient relaxation time is required for battery electrochemical equilibrium before the impedance measurement. A detailed experiment is performed to investigate the regularity of the battery impe...

The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors involved in various diseases including human cancer. As such, they have become important targets for therapeutic intervention. Cell-based receptor assays, able to detect agents that modulate receptor activity, are of key importance for drug discovery. We evaluated the potential of cellular electric impedance for this...

The present study describes a measurement-based model of electric image generation in the weakly electric mormyrid fish Gnathonemus petersii. Measurements of skin impedance, internal resistivity and fish body dimensions have been used to generate an electrical-equivalent model of the fish and to calculate electrical images and equivalent dipole sources for elementary resistive objects. These ca...