Electrospinning is a very simple and versatile process by which polymer nanofibers with diameters ranging from a few nanometers to several micrometers can be produced using an electrostatically driven jet of polymer solution or polymer melt. Significant progress has been made in this process throughout the past few years and electrospinning has advanced its applications in many fields, includin...

Magnetic nanofiber has been widely applied in biomedical fields due to its distinctive size, morphology, and properties. We proposed a novel needleless electrospinning method to prepare magnetic nanofibers from the self-assembling "Taylor cones" of poly(vinyl pyrrolidone) (PVP)/Fe₃O₄ ferrofluid (PFF) under the coincident magnetic and electric fields. The results demonstrated that a static PFF R...

The development of protein-based vaccines remains a major challenge in the fields of immunology and drug delivery. Although numerous protein antigens have been identified that can generate immunity to infectious pathogens, the development of vaccines based on protein antigens has had limited success because of delivery issues. In this article, an acid-sensitive microgel material is synthesized ...

The paper describes a protocol to fabricate cell-laden microgel assemblies with pre-defined micro-architecture and complexity by a bottom-up approach, which can be used for tissue engineering applications. The assembly process was driven by the hydrophobic effect in the water/oil interface. By agitating hydrophilic microgels in hydrophobic medium, the shape-controlled microgel units assemble in...

Crater-like electrospinning is a novel and cost-effective method for the mass scale production of nanofibers. The gas channel in the polymer solution plays a key role to produce a bubble Taylor cone or a crater-like Taylor cone, which is the key to eject the thin fluid jets (finally solidified into nanofibers) in electrospinning process. However, the formation mechanism of gas channel of crater...

INTRODUCTION Periodontitis is a chronic infectious disease and is the major cause of tooth loss and other oral health issues around the world. Periodontal tissue regeneration has therefore always been the ultimate goal of dentists and researchers. Existing fabrication methods mainly focused on a top-down tissue engineering strategy in which several drawbacks remain, including low throughput and...

Very thin liquid jets can be obtained using electric field, whereas an electrically-driven bending instability occurs that enormously increases the jet path and effectively leads to its thinning by very large ratios, enabling the production of nanometre size fibres. This mechanism, although it was discovered almost one century ago, is not yet fully understood. In the following study, experiment...

Widenbring, R. 2015. Microgel Interactions with Peptides and Proteins. Consequence of Peptide and Microgel Properties. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 196. 65 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9157-4. Microgels are lightly cross-linked hydrogel particles in the sub-micrometer to micrometer size range with a capacit...

DOI: 10.1002/adma.200904189 Microgels are particles made by chemically cross-linking a polymer to form particles of a gel that are colloidal in size. [ 1 , 2 ] Like their macroscopic counterparts, microgels can be swollen by a solvent, the degree of swelling depending on solvent quality and cross-link density. [ 3 , 4 ] As the solvent quality is governed by external stimuli such as temperature,...