Most mammals tested, when exposed to increasing pressure in helium/oxygen atmospheres, exhibit progressive motor disturbances culminating in two, usually successive, well-differentiated convulsive seizures. The seizures are highly reproducible components of the constellation of events that collectively constitute the High Pressure Neurologic Syndrome (HPNS). In the present study, we present evi...

The likelihood approach is common in linkage analysis of large extended pedigrees. Various peeling procedures, based on the conditional independence of separate parts of a pedigree, are typically used for likelihood calculations. A peeling order may significantly affect the complexity of such calculations, particularly for pedigrees with loops or when many pedigrees members have unknown genotyp...

Forty years ago, Steven G. Vandenberg and I founded Behavior Genetics (Vandenberg and DeFries 1970). Because one of the most frequently cited articles in human genetics (Haseman and Elston 1972) was published in the first issue of Volume 2 of this journal, its current Executive Editor, John K. Hewitt, agreed that this might be an appropriate time to share my recollections regarding the publicat...

It has been well documented that certain cognitive abilities decline as a function of the aging process, including episodic memory, processing speed, and inhibitory control. The rate at which espisodic memory and speed of processing change as a function of age is dependent upon a number of variables including health, education, and occupational complexity (Avolio & Waldman, 1994; Cagney & Laude...

17 18 The responses of canopy conductance to variation in solar radiation, vapour pressure deficit and soil 19 moisture have been extensively modelled using a Jarvis-Stewart (JS) model. Modelled canopy 20 conductance has then often been used to predict transpiration using the Penman-Monteith (PM) 21 model. We previously suggested an alternative approach in which the JS model is modified to 22

Overt computational constraints in the formation of mixed models for the analysis of large extended-pedigree quantitative trait data which allow one to reliably characterize and partition sources of variation resulting from a variety sources have proven difficult to overcome. The present paper suggests that by combining a restricted patterned covariance matrix approach to modeling and partition...