نتایج جستجو برای: encapsulated efficiency

تعداد نتایج: 403220  

Introduction: Nano-liposomes are Nano particulate vesicles with lipoid membrane which are under extensive investigation as drug carriers for improving the delivery of therapeutic agents. This study intended to enhance efficacy of Silibinin herbal drug in Nano liposome system (Nano phytosome) via encapsulation for delivery to liver cancer cells. Silibinin is one of the anti-cancer drugs, whi...

2012
Zhenning Cao Fangyuan Chen Ning Bao Huacheng He Peisheng Xu Saikat Jana Sunghwan Jung Hongzhen Lian Chang Lu

Droplet microfluidics provides a high-throughput platform for screening subjects and conditions involved in biology. Droplets with encapsulated beads and cells have been increasingly used for studying molecular and cellular biology. Droplet sorting is needed to isolate and analyze the subject of interest during such screening. The vast majority of current sorting techniques use fluorescence int...

Journal: :International journal of molecular medicine 2014
Yiqun Han Peng Zhang Yuanyuan Chen Jiping Sun Fansheng Kong

The co-delivery of DNA and antitumor drugs has the potential to treat cancer. In this study, we aimed to develop surface-modified, co-encapsulated solid lipid nanoparticles (SLN) containing enhanced green fluorescence protein plasmid (pEGFP) and doxorubicin (DOX) in order to create a multifunctional delivery system that targets lung cancer cells, in an effort to improve the efficacy of cancer t...

2014
X. Pan H. Wang

Introduction Conclusions References Tables Figures

Journal: :Journal of immunological methods 1994
H F Savelkoul R van Ommen A C Vossen E G Breedland R L Coffman A van Oudenaren

The availability of cell lines that are transfected with IL-4, IL-5 and IFN-gamma cytokine genes permits the prolonged in vivo delivery of functional cytokines in relatively large doses for the modulation of specific immune responses. Often the transfected cells are xenogeneic or allogeneic to the experimental animal and have to be encapsulated in such a way that no cellular response by the hos...

Journal: :Lab on a chip 2013
Zhenning Cao Fangyuan Chen Ning Bao Huacheng He Peisheng Xu Saikat Jana Sunghwan Jung Hongzhen Lian Chang Lu

Droplet microfluidics provides a high-throughput platform for screening subjects and conditions involved in biology. Droplets with encapsulated beads and cells have been increasingly used for studying molecular and cellular biology. Droplet sorting is needed to isolate and analyze the subject of interest during such screening. The vast majority of current sorting techniques use fluorescence int...

2014
Jae-Ho Lee Shuai Shao Kenneth T. Cheng Jonathan F. Lovell Chang H. Paik Warren G. Magnuson

Porphyrin–lipid nanovesicles (PLN) have been developed with intrinsic capabilities as activatable multimodal photonic contrast agents. Radiolabeling of PLN encapsulating drugs could eventually be able to provide quantitative in vivo information for diagnosing and treating diseases. In this study, we developed Tc-labeled porphyrin–lipid nanovesicles (Tc-PLN) as a cargo-encapsulated formulation w...

Journal: :Current pharmaceutical biotechnology 2014
Victor M Balcao Milca G Santos Paloma R Martins Marco V Chaud Jose M de Oliveira Junior Matthieu Tubino Marta M D C Vila

Nitrofurazone (NTZ) is usually employed in the topical treatment of infected wounds and lesions of both skin and mucosa. Microencapsulation is a process utilized in the incorporation of active ingredients within polymers aiming at, among other objectives, the prolonged release of pharmaceutical compounds and protection from atmospheric agents (viz. moisture, light, heat and/or oxidation). With ...

Journal: :Journal of pharmaceutical sciences 2007
Mahesh D Chavanpatil Ayman Khdair Yogesh Patil Hitesh Handa Guangzhao Mao Jayanth Panyam

Poor drug encapsulation efficiency and rapid release of the encapsulated drug limit the use of nanoparticles in biomedical applications involving water-soluble drugs. We have developed a novel polymer-surfactant nanoparticle formulation, using the anionic surfactant Aerosol OT (AOT) and polysaccharide polymer alginate, for sustained release of water-soluble drugs. Particle size of nanoparticles...

2016
Mohammad Mahdi Ochi Ghasem Amoabediny Seyed Mahdi Rezayat Azim Akbarzadeh Bahman Ebrahimi

OBJECTIVE This study aimed to evaluate a co-encapsulated pegylated nano-liposome system based on two herbal anti-tumor drugs, silibinin and glycyrrhizic acid, for delivery to a hepatocellular carcinoma (HCC) cell line (HepG2). MATERIALS AND METHODS In this experimental study, co-encapsulated nano-liposomes by the thin layer film hydration method with HEPES buffer and sonication at 60% amplitu...

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