BACKGROUND Diastolic filling at rest is altered markedly with advancing age. Whether exercise training can improve diastolic filling at rest or during exercise in either healthy older or healthy young men has not been determined. The purpose of this study was to determine if 6 months of aerobic exercise training improves diastolic filling. METHODS AND RESULTS Radionuclide diastolic filling pa...

End-users often have to enter the same information to various services (e.g., websites and mobile applications) repetitively. To save end-users from typing redundant information, it becomes more convenient for an end-user if the previous inputs of the end-user can be prefilled to applications based on end-user’s contexts. The existing pre-filling approaches have poor accuracy of pre-filling inf...

In early diastole, pressure is lower in the apex than in the base of the left ventricle (LV). This early intraventricular pressure difference (IVPD) facilitates LV filling. We assessed how LV diastolic IVPD and intraventricular pressure gradient (IVPG), defined as IVPD divided by length, scale to the heart size and other physiological variables. We studied 10 mice, 10 rats, 5 rabbits, 12 dogs, ...

background: one ideal property of a root-end fi lling material is its apical sealing ability. the aim of this in vitro study was to assess bacterial and dye microleakage of white and gray mineral trioxide aggregate (wmta and gmta), portland cement and calcium-enriched mixture (cem) cement used as root-end fi lling material, and to assess the agreement between these two test methods. materials a...

introduction : the purpose of this clinical study was to compare the blood mercury levels before and after endodontic surgery using amalgam as a root-end filling material. materials and methods: fourteen patients requiring periradicular surgery participated in this prospective clinical study. a zinc-free amalgam was employed as root-end filling material. blood samples were collected at three in...

BACKGROUND The present study was aimed to evaluate and compare the apical sealing ability of two endodontic root-end filling materials namely, iRoot SP (ceramic based) and ProRoot MTA using the bacterial leakage system. MATERIAL AND METHODS A total of fifty recently extracted, single rooted teeth with a single straight canal were selected for the study. The teeth were chemo mechanically prepa...

OBJECTIVES We sought to assess the prognostic value of left ventricular (LV) filling patterns, as determined by mitral E-wave deceleration time (DT) and color M-mode flow propagation velocity (Vp), on cardiac death and serial changes in LV volumes after a first myocardial infarction (MI). BACKGROUND Combined assessment of DT and Vp allows separation of the effects of compliance and relaxation...

XLF/Cernunnos is a core protein of the nonhomologous end-joining pathway of DNA double-strand break repair. To better define the role of Cernunnos in end joining, whole-cell extracts were prepared from Cernunnos-deficient human cells. These extracts effected little joining of DNA ends with cohesive 5' or 3' overhangs, and no joining at all of partially complementary 3' overhangs that required g...