OBJECTIVE To determine if amoxicillin/clavulanate potassium is effective in the treatment of Chlamydia trachomatis endocervicitis. METHODS Thirty-two patients with culture-proven endocervical infection were treated with amoxicillin/clavulanate potassium, 500 mg orally 3 times a day for 10 days. Post-treatment endocervical specimens were obtained at 2, 4, and 6 weeks for culture of C. trachoma...

To test for the presence of Neisseria gonorrhoeae infection, culture speciments were taken from the endocervical, urethral, and rectal sites in 556 women seen at the Alameda County Venereal Disease Clinic, Oakland, California, U.S.A. There was no significant difference between the number of new cases found with the rectal speciments alone (nine out of a total of 154 cases diagnosed) and those r...

INTRODUCTION Trichomonas vaginalis infection is associated with an increased risk of HIV infection in exposed-seronegative women (ESN) despite their unique immune quiescent profile. It is important to understand possible mechanisms, such as recruitment of activated T cells, by which T. vaginalis could facilitate HIV infection in this population. METHODS We conducted a cross-sectional study ex...

The performance characteristics of the new signal amplification-based Hybrid Capture (HC) II CT-ID test system (Digene, Silver Spring, Md.) with endocervical specimens were compared to those of tissue culture and PCR (AMPLICOR CT PCR; Roche Molecular Systems, Branchburg, N.J.) for detection of Chlamydia trachomatis in 587 women. HC II CT-ID identified 62 of 65 confirmed C. trachomatis-positive ...

Background. Persistently high incidence of cervical cancer in Russia and significant number cases detected the late stages necessitate improvement secondary prophylaxis this disorder. Aim. To assess risk factors for recurrent high-grade intraepithelial neoplasia (CIN2+) (high grade squamous lesions, HSIL) after conization. Materials methods. This study included 62 patients with HSIL treated Nov...

The objective of this study is to assess the value of postcone endocervical curettage, after conization of cervical intraepithelial neoplasia or carcinoma as a predictive tool for residual lesions. This is a retrospective observational study. All data were obtained by the University Hospital of Zurich, Department of Gynaecology. One hundred fifty patients underwent hysterectomy within 12 months...

BACKGROUND AND OBJECTIVES Ureaplasma urealyticum can colonize women genital tract and be isolated from the amniotic fluid of women with adverse pregnancy outcomes. The association of U. urealyticum with spontaneous abortion remains controversial. The aim of this study was to evaluate the frequency of U. urealyticum infection among pregnant women and its association with spontaneous abortion. ...

The importance of cervical squamous metaplasia and human papillomavirus 16 (HPV 16) infection for cervical carcinoma has been well established. Nearly 87% of the intraepithelial neoplasia of the cervix occur in the transformation zone, which is composed of squamous metaplastic cells with unclear origin. HPV DNA, mostly HPV 16, has been found in 90% of cervical carcinomas, but only limited exper...

Uterus Didelphys, a Congenital anomaly of uterus with a soft vertical vaginal septum reported to the Gynec OPD with complaint of irregular post menopausal bleeding and offensive vaginal discharge. On examination, found to have two uterus and two cervices with a soft vertical vaginal septum and endocervical polyp of 5x3 cm size, was found in one of the cervix which was pedunculated and bleeding ...