Introduction: The process of discriminating among benign and malignant hyperplasia begun with subjective methods using light microscopy and is now being continued with computerized morphometrical analysis requiring some features. One of the main features called Volume Percentage of Stroma (VPS) is obtained by calculating the percentage of stroma texture. Currently, this feature is calculated ...

OBJECTIVE To conduct a meta-analysis of the studies assessing the effects of mifepristone on the uterus, uterine leiomyoma, and leiomyoma-related symptoms in premenopausal women. DESIGN Meta-analysis. SETTING Centers for reproductive care. PATIENT(S) Premenopausal women who suffered from leiomyoma. INTERVENTION(S) We identified all of the studies published before December 2012 that comp...

OBJECTIVE To monitor the effects of raloxifene therapy on the uterus of postmenopausal women by transvaginal ultrasonography and color flow Doppler. METHODS Twenty-five healthy postmenopausal women were enrolled in this prospective longitudinal study performed at Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto. The patients were treated with raloxifene hydrochlo...

OBJECTIVE Patient chances for cure and palliation for a variety of malignancies may be greatly affected by the care provided by a treating hospital. We sought to determine the effect of volume and teaching status on patient outcomes for five gynecologic malignancies: endometrial, cervical, ovarian and vulvar carcinoma and uterine sarcoma. METHODS The Florida Cancer Data System dataset was que...

BACKGROUND Although embryo implantation is a prerequisite for human reproduction, it remains a poorly understood process. The molecular mechanisms regulating endometrial receptivity and/or embryo implantation are still largely unclear. METHODS Pubmed and Medline literature databases were searched for articles in English published up to December 2013 with relevant keywords including 'endometri...

BACKGROUND The selective progesterone receptor modulator asoprisnil suppresses uterine bleeding and decreases leiomyoma volume while maintaining follicular phase estrogen concentrations. For safety of potential clinical applications, any proliferative effect of asoprisnil on uterine tissues, particularly endometrium, needs to be established. METHODS In a double-blind, randomized, placebo-cont...

Background: The aim of this study is to evaluate whether the location of the balloon placement into either the cervical canal or uterine cavity during sonohysterography can affect the intensity of pain. Materials and Methods: A total of 300 infertile women undergoing sonohysterography were randomized to intracervical or intrauterine balloon placement. The examination was scheduled in the early ...

PURPOSE To study the diagnostic accuracies of serum human epididymis protein 4 (HE-4) levels, virtual organ computer-aided analysis (VOCAL) parameters and endometrial volume in endometrial cancer cases. MATERIALS AND METHODS One hundred and seven patients (37 with endometrial cancer and 70 with benign endometrial pathology) were included in this study. VOCAL parameters and serum HE-4 levels w...

objective: endometriosis is a common disease in which the endometrial stroma and glands grow abnormally outside the uterine cavity. the establishment of animal models can be effective for determining the etiology of endometriosis. in this study we compare two endometriosis models using endometrial fragments and isolated cultured endometrial cells. methods: we obtained endometrial tissues that ...