akbar pirestani,*, mohammad javad bagheri, sayed mahdi hashemi, amir hossine asgarishahi   department of animal science, khorasgan (isfahan) branch, islamic azad university, isfahan, iran     *corresponding author: email: [email protected]     received: 20 july 2013   accepted: 21 november 2013       abstract this study was conducted to evaluate the impact of se+vit e and cu injection on...

PURPOSE To describe a novel method of global cell viability assessment for Descemet membrane endothelial keratoplasty (DMEK) and the comparison of two contemporary methods of donor tissue preparation. METHODS DMEK transplants were prepared using two different methods: liquid bubble separation and manual peeling (n=8 each group). Samples were incubated with Hoechst, calcein-AM and ethidium hom...

objective: in this investigation murine embryonic stem (es) cells were differentiated into endothelial cells. materials and methods: murine es cells (cce cell line) exposed to alpha-mem medium containing 10% fbs for 4 days. then obtained flk-1 (flk-1: vascular endothelial growth factor receptor 2) positive cells were cultuted in endothelial growth medium-2 (egm-2) until the last day of experime...

infection with human immunodeficiency virus (hiv) is a progressive condition which may cause endothelial dysfunction and liver damage leading to coagulopathy. with adventure of highly active antiretroviral therapy (haart), life expectancy has prolonged in hiv positive patients but several acquired immunodeficiency syndrome (aids)-related conditions such as coagulopathies are responsible for ass...

Background: Radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (AVM) may be used as markers for specific vascular targeting agents. In this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...

The purpose of the study was to investigate the changes in the endothelial cell count and cell’s polymegathism and pleomorphism after selective laser trabeculoplasty (SLT) in open-angle glaucoma (OAG). SLT has been performed on 18 patients (22 eyes). Each patient underwent confocal microscopy 1 h prior to the laser surgery and then 1 h, 1 day, 1 week, and 1 month after SLT. The obtained microgr...

littoral cell angioma is a splenic vascular tumor of splenic sinus lining cells that is considered benign in general. this report describes a case of littoral cell angioma with no malignant histological features. the lesion is composed of anastomosing vascular channels resembling splenic sinus; they are lined by endothelial cells which show mitotic activity very rare. immunohistochemically, the...

Thrombotic thrombocytopenic purpura (TTP) is a type of microangiopathy, which characterized by the formation small blood clots in vessels, leading to organ damage and low platelet count. In sickle cell disease (SCD), TTP can occur due activation coagulation system endothelial cells lining vessels. The importance SCD lies its potential cause severe life-threatening complications, including strok...