Abstract Background Cardiac involvement is a major cause of death in patients with systemic sclerosis (SSc). Epicardial adipose tissue (EAT) has recently emerged as mediator between inflammatory disorders and cardiovascular disease, may therefore play role the pathophysiology cardiac SSc. Purpose To assess correlation EAT mass left ventricular (LV) function, to determine prognostic value Method...

Currently, research on understanding adipose tissue (AT) metabolism has increased significantly. AT is an endocrine organ, that releases proteins, specific metabolites, hormones, micro-RNAs and signaling lipids, all involved in a network of inter-organ communication. Among other effects, dysfunction contributes to proinflammatory diabetogenic state, from early stage the disease development. Ove...

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