background and aims: ebv is a human herpesvirus that infects more than 90% of the world’s population. although, benign and asymptomatic for most cases, the infection can cause many nonmalignant and malignant disorders of lymphoid and epithelial origins. the objective of this study was detection of im prevalence in neyshabur, northeast iran from 2010-2014.   materials and methods: this cross-sec...

introduction: ebv is categorized as herpesviridans and by nature is a lymph crypto virus. studies have demonstrated that ebv will infect 80 to 90 percent of patients during the first year and there is a close relation between kidney malfunction and ebv infection. reactivation of the virus excites the immune system, and ultimately leads to rejection of kidney. the purpose of this study was to de...

background: breast cancer is the most common malignancy in females worldwide. several etiological factors including environmental factors have been recognized for breast cancer. epstein barr virus as a viral etiological factor has been proposed. so far, several studies have investigated the relationship between development of breast cancer and epstein barr virus, but few have been done in iran....

Immunoglobulin M (IgM) antibodies to Epstein-Barr virus were detected by using microtiter plates coated with anti-mu-chain antiserum and enzyme-labeled Epstein-Barr virus antigen. Optimum conditions for labeling were determined. The addition of unlabeled control antigen to the enzyme-labeled antigen was effective in reducing background reactions. Rheumatoid factor no longer interfered. Blocking...

We report a patient with X-linked lymphoproliferative disease (XLP) who developed multiple central nervous system (CNS) manifestations of Epstein-Barr virus infection. XLP, or Duncan syndrome, is a rare inherited disorder characterized by the inability to clear Epstein-Barr virus infection. In addition to Epstein-Barr virus encephalitis, CNS lymphoproliferative disease, and lymphoma, this patie...

Prior studies have shown that patients with seropositive rheumatoid arthritis (RA) have an increased frequency of precipitating antibody against a nuclear antigen, the RA nuclear antigen, detected in human B lymphoblastoid cell lines infected by Epstein-Barr virus. The present investigations demonstrate that patients with seropositive RA also have specifically elevated titers of antibodies to a...

BACKGROUND Mortality caused by cardial gastric cancer in Chile, is increasing. Previously we demonstrated an association between Epstein Barr virus and this specific location of gastric cancer. AIM To perform a clinical and molecular characterization of cardial gastric cancer associated to Epstein Barr virus. MATERIAL AND METHODS Epstein Barr virus was identified in 93 cardial gastric tumor...

INTRODUCTION We present a case of an unusual clinical manifestation of Guillain-Barre syndrome following a pre-existing herpes virus infection. Although there have been several reports describing the co-existence of herpes virus infection and Guillain-Barre syndrome, we undertook a more in-depth study of the cross-reactivity between herpes viruses and recommend a follow-up study based on serolo...

Various autoantibodies have been reported to be detected during the progression of infectious mononucleosis. We observed a case of infectious mononucleosis due to Epstein-Barr virus primary infection for 2 months, and noticed the transiently increased titer of thyrotropin receptor autoantibodies detected at the acute phase on the 3rd day after admission. At that time, real-time quantitative PCR...

A technique using indirect immunoperoxidase antibody was developed for the detection of specific serum IgA antibody to Epstein-Barr virus capsid antigen and early antigen. The IgA technique was compared with an immunofluorescence antibody method. Epstein-Barr virus IgA antibody against viral capsid antigen was detected in all nine patients with Epstein-Barr virus associated undifferentiated nas...