This report summarizes the evidence that the control of the concentration of free calcium ions in body fluids is centered at mineralized bone surfaces. This process involves an increase in the solubility of bone mineral produced by the non-collagenous proteins existing in the bone extracellular fluid (ECF) and on the adjacent surfaces of bone. The result is a basic equilibrium level produced in...

In this study, we use solubility and drop-solution calorimetry measurements to determine the thermodynamic properties of the uranyl phosphate phases autunite, uranyl hydrogen phosphate, and uranyl orthophosphate. Conducting the solubility measurements from both supersaturated and undersaturated conditions and under different pH conditions rigorously demonstrates attainment of equilibrium and yi...

We analyzed the physicochemical characteristics of solid dispersions of pizotifen malate and povidone (Kollidon 12) at different proportions; we used X-ray diffraction, infrared spectrometry and differential scanning calorimetry (DSC) and tested the solubility of the solid dispersions in equilibrium. The results were compared with findings for physical mixtures with the same proportions. A soli...

A new methodology for determining simultaneous chemical and phase equilibrium of mixtures of light gases and aqueous electrolyte solutions with the potential for multiple salt deposition is proposed. The novel aspects of this new approach include, but are not limited to (1) a novel tearing algorithm for determining equilibrium ion solubility limits, (2) rigorous proof that the proposed tearing ...

The design and development of processes involving supercritical fluids depend on how easy the phase equilibrium can be accurately modelled and predicted. In the work described herein, the supercritical fluid-solid equilibrium has been considered. Modelling the fluid-solid equilibrium is associated with a number of drawbacks, even when it is possible to obtain the experimental solubility data fo...

The influence of change of temperature on the carbonic acidbase-protein equilibrium in blood or serum involves three factors: (1) Change in solubility of CO2 in serum or blood. (2) Change in the equilibrium constants of the buffer systems in the blood. (3) Change in the equilibrium constant for the dissociation of water. The fact that the solubility of CO2 changes with temperature has naturally...