We report the rare occurrence of erythema nodosum and pyoderma gangrenosum at different times during the clinical course in a 30-year-old gentleman. He initially presented with biopsyproven erythema nodosum over both shins. He subsequently developed multiple violaceous and vegetative nodules over the upper and lower limbs. Three serial skin biopsies were performed thereafter. A diagnosis of veg...

Erythema nodosum leprosum necroticans is an uncommon manifestation of type 2 lepra reaction, encountered in lepromatous and borderline lepromatous cases of leprosy. We report an unusual clinical presentation of necrotic erythema nodosum leprosum in a 9-year-old boy with no pre-existing evidence of leprosy. The lesions resolved completely following multi-bacilliary multi-drug therapy for 12 mont...

Contrary to their undoubted efficacy on rheumatologic diseases, potential for developing skin lesions with Tumor necrosis alpha blockers (Anti-TNF alpha) is an important question in our minds. Although we know, most of the studies and case reports in the literature show that adalimumab is an effective treatment agent on erythema nodosum, we should keep in mind this lesion as a rare paradoxical ...

BACKGROUND Possibly any tumor that can cause mechanical obstruction of the distal bile duct can induce acute pancreatitis. However, acute pancreatitis as the first clinical manifestation of duodenal lymphoma is extremely rare. OBJECTIVE To report the case of a patient with acute pancreatitis as an extremely rare first manifestation of duodenal MALT lymphoma and possible association with eryth...

Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve sig...

Sarcoidosis is a systemic disorder in which cutaneous findings are often prominent. These may be polymorphous to the extent that sarcoidosis may mimic many other cutaneous diseases. We describe a 56-year-old woman with involvement of the skin, eyes, bones, heart, and lung. After an initial presentation 10 years earlier of erythema nodosum with bilateral hilar adenopathy, there were three types ...

A 22-year-old woman who previously diagnosed Crohn’s disease was admitted with a 1-month history of diarrhea. She reported that during the preceding 3 months, she had stopped taking her drugs for Crohn’s disease. She was not able to tread on her left foot. On examination, there was an erythematous, non-purpuric, painful, slightly nodular and, 3-4 cm diameter lesion (Figure 1). Plantar erythema ...