نتایج جستجو برای: esophageal adenocarcinoma

تعداد نتایج: 104941  

Journal: :Surgical oncology clinics of North America 2009
Gary W Falk

The incidence of esophageal adenocarcinoma is increasing at a rate greater than that of any other cancer in the Western world today. Barrett's esophagus is a clearly recognized risk factor for the development of esophageal adenocarcinoma, but the overwhelming majority of patients with Barrett's esophagus will never develop esophageal cancer. To date, dysplasia remains the only factor useful for...

2009
Hushan Yang Jian Gu Kenneth K. Wang Wei Zhang Jinliang Xing Zhinan Chen Jaffer A. Ajani Xifeng Wu

Purpose: Esophageal adenocarcinoma is a highly aggressive malignancy that frequently develops from Barrett's esophagus, a premalignant pathologic change occurring in the lower end of the esophagus. Identifying Barrett's esophagus patients at high risk of malignant transformation is essential to the prevention of esophageal adenocarcinoma. Although microRNA (miRNA) expression signatures have bee...

A. Shafaghi, H. Froutan, M.S. Keshmiri,

 Abstract Background: Esophageal cancer is one of the major malignancies, with various epidemiological aspects in recent years in developing countries, including increased prevalence and variations of pathologic patterns. This may be due to increasing rates of Barrett’s esophagus, gastroesophageal reflux, smoking and obesity. This study was performed from 1991 to 2005 in order to evaluate vario...

Journal: :Clinical Gastroenterology and Hepatology 2006

2011
D. Dellaportas P. Lykoudis G. Gkiokas G. Polymeneas A. Kondi-Pafiti D. Voros

Introduction. In patients with extra-adrenal malignancy, an adrenal mass necessitates investigating the possibility of metastatic tumor. Curable adrenal metastasis are considered as a rare event. Case report. A 52-year-old male suffering from lower esophageal adenocarcinoma with a solitary left adrenal metastasis is presented herein, who underwent concomitant transhiatal esophagectomy and left ...

2014
Zhiqiang Wang Thiago G. Da Silva Ke Jin Xiaoqing Han Prathibha Ranganathan Xiaoxia Zhu Avencia Sanchez-Mejias Feng Bai Bin Li Dennis Liang Fei Kelly Weaver Rodrigo Vasquez-Del Carpio Anna E. Moscowitz Vadim P. Koshenkov Lilly Sanchez Lynne Sparling Xin-Hai Pei Dido Franceschi Afonso Ribeiro David J. Robbins Alan S. Livingstone Anthony J. Capobianco

Esophageal adenocarcinoma ranks sixth in cancer mortality in the world and its incidence has risen dramatically in the Western population over the last decades. Data presented herein strongly suggest that Notch signaling is critical for esophageal adenocarcinoma and underlies resistance to chemotherapy. We present evidence that Notch signaling drives a cancer stem cell phenotype by regulating g...

Journal: :Cancer research 2014
Zhiqiang Wang Thiago G Da Silva Ke Jin Xiaoqing Han Prathibha Ranganathan Xiaoxia Zhu Avencia Sanchez-Mejias Feng Bai Bin Li Dennis Liang Fei Kelly Weaver Rodrigo Vasquez-Del Carpio Anna E Moscowitz Vadim P Koshenkov Lilly Sanchez Lynne Sparling Xin-Hai Pei Dido Franceschi Afonso Ribeiro David J Robbins Alan S Livingstone Anthony J Capobianco

Esophageal adenocarcinoma ranks sixth in cancer mortality in the world and its incidence has risen dramatically in the Western population over the last decades. Data presented herein strongly suggest that Notch signaling is critical for esophageal adenocarcinoma and underlies resistance to chemotherapy. We present evidence that Notch signaling drives a cancer stem cell phenotype by regulating g...

2013
Sudhir K Dutta Kireet Agrawal Mohit Girotra Steven Fleisher Mahnaz Motevalli Mitchell A Mah’moud Padmanabhan P Nair

Barrett’s esophagus is well recognized as a premalignant condition leading to higher incidence of esophageal adenocarcinoma than the general population (Cameron, 1995; Katz, 1998; Solaymani-Dodaran, 2004). The risk of esophageal adenocarcinoma is approximately 30 times greater in patients with Barrett’s esophagus as compared with the general population (SolaymaniDodaran, 2004). Barrett’s esopha...

2001
Ju Ik Son Hyo Jin Park Kee Sup Song Ki Joong Kim Chang Youl Lee Sang In Lee In Suh Park

BACKGROUND Adenocarcinoma of the esophagus has been reported to be increasing in incidence in a number of regions throughout the world, while the incidence of squamous cell carcinoma (SCCA) of the esophagus is mostly stable or decreasing. To evaluate the increasing tendency of adenocarcinoma of the esophagus. METHODS We studied retrospectively the records of patients with histologically prove...

Journal: :Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2008
D Vallböhmer A H Hölscher J Brabender K Prenzel C Gutschow W Schröder R Metzger E Bollschweiler

Evidence suggests a significant difference in the incidence, presentation, and outcome of young and elderly patients with esophageal adenocarcinoma. We aimed to compare clinicopathologic and prognostic factors of young and elderly patients with esophageal adenocarcinoma at a surgical department in Europe. From 1996 to 2006, 223 patients with a resectable esophageal adenocarcinoma were analyzed ...

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